Indian red scorpion (Mesobuthus tamulus; MBT) produces lethal stings and is a matter of concern in certain parts of India. MBT envenomation produces multi-systemic involvement, thus presents difficulty in the management. Symptomatic treatment has been practiced earlier that failed to relieve the toxic effects of the venom. Therefore, present manuscript deals with pathophysiologically based appr...

conclusions our data suggest that using polyvalent antivenom in short time after envenomation could reduce the inflammatory responses related to the systemic changes during the elevation of cytokines in scorpion envenomation. results il-1a, il-6, and tnf-α levels were significantly increased in 3 hours after envenomation in both groups (v and av), but the intensity of increase in av group was l...

INTRODUCTION The preponderance of medical literature regarding severe bark scorpion envenomation describes pediatric patients; however, the majority (>66%) of annual poison center calls pertain to adults. This retrospective review sought to evaluate the clinical manifestations of adults with severe Centruroides sculpturatus envenomation and determine if significant morbidity occurred. METHODS...

Venom of Leiurus abdullahbayrami (Scorpiones: Buthidae) is an extremely toxic one and it stimulates voltage-gated sodium and potassium channels. In case of a stung by this scorpion; excessive catecholamine release occur and it impairs left ventricle contractility and consequently a heart failure occurs (scorpion sting-related cardiomyopathy). In addition to this cardiac-induced acute pulmonary,...

We describe a case of severe scorpion envenomation in an adult patient, with the presence of very rapid sustained ventricular tachycardia followed by cardiogenic shock, which was reversed by scorpion antivenom administration. Scorpion venom causes cardiac changes that can lead to an environment favoring arrhythmogenesis.

In Algeria scorpion envenomation represents a real public health problem with a population at risk of scorpion stings estimated at 68% of the national population. A total of 903, 461 scorpion sting cases and 1996 deaths were recorded by health services between 1991 and 2012. The physical-geographic and climate conditions make the province of Naama a conducive environment for scorpion species an...

Scorpion stings are a common occurrence in Saudi Arabia. The majority of cases present with local pain at the site of envenomation, and follow a benign clinical course. Severe systemic toxicity and mortality are uncommon. Reported deaths have been attributed to a primary effect of the venom on the cardiovascular system. Toxicity of envenomation varies between species and within the same species...

Introduction Accidental scorpion sting is a serious health issue of poor communities in tropical and subtropical areas throughout the world. Out of 1500 scorpion species distributed throughout the world, only 50 scorpion species have been proved lethal to human [1]. The symptoms of scorpion envenomation depend on species, age, venom composition and the victim’s physiological response. Scorpion ...

OBJECTIVE Scorpion antivenom was recently approved for use in patients with clinically significant scorpion envenomation in the United States; no formal economic analysis on its impact on cost of management has been performed. METHODS Three different strategies of management of scorpion envenomation with systemic neurotoxic symptoms in children were compared for cost minimization from a socie...