PURPOSE In this study, we investigated the penetration of various proteins into the mouse eye after a periocular injection of the protein or an adenoviral vector (Ad) expressing the protein. METHODS At several time points after the injection, the retina, retinal pigmented epithelium/choroid, and sclera were dissected and enzyme-linked immunosorbent assays were performed. RESULTS After a per...

Supplemental intravitreal gas injection was used in the early postoperative period in an attempt to achieve long term retinal reattachment in 11 cases of failed scleral buckling surgery. Success was dependent on the presence of a correctly placed scleral buckle underlying all breaks. Surgical revision was thereby avoided in these patients. However, when the scleral buckle was inadequate the tec...

PURPOSE To evaluate the macular choroidal and scleral changes in tilted disc syndrome (TDS) with staphyloma using optical coherence tomography (OCT) to determine the mechanism of serous retinal detachment (SRD) formation. METHODS All eyes underwent fluorescein (FA) and indocyanine green angiography (ICGA) in this retrospective, observational study. Enhanced-depth imaging (EDI) OCT and prototy...

Mitomycin (MMC) has been associated with a variety of complications, including corneoscleral melt. We report the successful repair of a scleral melt with a partial thickness autologous scleral graft of the scleral melting. A 55-year-old male patient underwent pterygium resection surgery and intraoperative MMC application. The patient developed a deep melting area that almost reached the choroid...

PURPOSE To report the outcomes of surgical refixation of posteriorly dislocated intraocular lens (IOL) using scleral-tuck method, and to compare the "scleral groove" and the "scleral flap" techniques used. STUDY DESIGN Single-center, retrospective, interventional, comparative study. METHODS Medical records of patients undergoing closed globe scleral refixation of posteriorly dislocated post...

The present study aimed to investigate the efficacy of tailored treatment for the management of scleral necrosis following pterygium surgery. A series of nine cases of scleral necrosis following pterygium excision between September 2009 and September 2012 were included. In cases where ischemia was the cause of scleral necrosis, Tenon's membrane covering (TMC) surgery was performed. For cases wi...

OBJECTIVE To present a comprehensive review of current and historical literature on scleral lenses. METHODS A comprehensive search of several databases from each database's earliest inception to May 23, 2014 was conducted by an experienced librarian with input from the author to locate articles related to scleral lens design, fabrication, prescription, and management. RESULTS A total of 899...

Scleral fixation of intraocular lenses (IOLs) can be performed under the protection of a scleral flap. A variation of this technique uses a scleral tunnel for suture fixation to the eye. Passage of a double-armed suture through the roof of the scleral tunnel with subsequent retrieval of the suture ends through the external incision for tying facilitates scleral fixation. This modification offer...

BACKGROUND Due to low energy levels in microphotodiode-based subretinal visual prostheses, an external power supply is mandatory. We report on the surgical feasibility and the functional outcome of the extraocular part of an approach to connect a subretinal prosthesis to an extracorporeal connector in the retro-auricular space via a trans-scleral, transchoroidal cable. METHODS Seven volunteer...