We are interested in the problem of restoring scintigraphic images acquired by the gamma detector in nuclear medicine. The aim is to improve the detectability of possible heterogeneous areas in different organs. We propose to solve the problem in the Bayesian framework with the Maximum A Posteriori (MAP) principle. The prior information was modeled by a Markov Random Field (MRF). The optimizati...

introduction:targeted radionuclide therapy (trt) has been demonstrated to be an effective therapeutic tool in patients with disseminated bone metastasis. trt is generally performed with a single radionuclide. in this study we investigated the feasibility of combined trt with a high-energy beta emitter (153sm) and a low energy beta emitter (177lu) in wistar rats. methods: the cocktail complex of...

Exercise thallium-201 myocardial scintigraphy was performed in 23 patients with hypertrophic cardiomyopathy. Eighteen patients presented with chest pain which was a persistent symptom in 11. Selective coronary arteriography was performed in 16 patients and showed normal coronary arteries in 15 and insignificant luminal irregularities in one patient. Eighteen patients had abnormal scintigrams. T...

In this study we evaluated two different""To-labeling techniques to produce "To-low density lipoprotein (Tc-LDL) suitable for the scintigraphic delineation of experimental atherosclerotic lesions. The two methods are 1) a procedure that uses stamnous chloride and sodium borohydride (borohydride method) and 2) a procedure that uses sodium dithiionite as a reducing agent and that has been success...

Myocardial involvement in progressive muscular dystrophy of the Duchenne type was evaluated in 19 patients using thallium-201 myocardial perfusion imaging. A qualitative analysis was performed from five projection images by three experienced physicians. Distinct perfusion defects were shown in 13 patients, especially in the LV posterolateral or posterior wall (11 patients). There was no signifi...

Scintigraphic imagery is widely used in nuclear medicine and in industrial testing. However, the image quality is very poor due to several degradations: Poisson noise, scattering of gamma photons, and non-stationary impulse response of the gamma detector. The restoration of scintigraphic images is typically an ill-posed inverse problem. In this paper, we propose a restoration method based on th...

Clinical, radiographic, and scintigraphic abnormalities of the knee joint have been correlated in a cross sectional study of 100 patients with osteoarthritis. The group comprised 73 women and 27 men with a mean age of 65.7 years. One hundred and ninety one of the 200 knees had clinical (175) or radiographic (185) evidence of osteoarthritis, or both (161). Scintigraphic images of the knees were ...

Epicardial phenol application or transmural myocardial infarction in dogs produces sympathetic denervation of myocardium apical to the site of the intervention. Because efferent denervation is probably postganglionic, reinnervation most likely occurs but has not been shown. We investigated whether 123I-labeled metaiodobenzylguanidine (MIBG), a norepinephrine analogue taken up by sympathetic ner...