Several authors have reported schistosomiasis caused by Schistosoma haematobium in the female genital tract of patients in endemic areas. This work describes tubal schistosomiasis by Schistosoma mansoni in a Brazilian woman submitted to hysterectomy for uterine myomatosis and metrorrhagia. Macroscopy evidenced hydrosalpinx of the left tube and multiple Schistosoma mansoni eggs were identified b...

BACKGROUND Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA1-3). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cells. Here we provide evidence for the role of LPA and LPA receptors in Th2-dominant airway inflammation. METHODS Wild type, LPA1 heterozygous knockout mice...

BACKGROUND In Africa, many areas are co-endemic for the two major Schistosoma species, S. mansoni and S. haematobium. Epidemiological studies have suggested that host immunological factors may play an important role in co-endemic areas. As yet, little is known about differences in host immune responses and possible immunological interactions between S. mansoni and S. haematobium in humans. The ...

Background: Schistosoma mansoni was observed and reported in Kuluva hospital Arua District in north western Uganda as early as 1902. S. mansoni is widely distributed in Uganda along permanent water bodies. Objective: To review the litreture on scistosomiasis in Uganda, since 1902. Method: The core literature for this short review was searched from reports and publications by the British colonia...

Schistosoma mansoni is a parasitic fluke that infects millions of people in the developing world. This study presents the first application of population genomics to S. mansoni based on high-coverage resequencing data from 10 global isolates and an isolate of the closely-related Schistosoma rodhaini, which infects rodents. Using population genetic tests, we document genes under directional and ...

CA88 is the first long nuclear repetitive DNA sequence identified in the blood fluke, Schistosoma mansoni. The assembled S. mansoni sequence, which contains the CA88 repeat, has 8,887 nucleotides and at least three repeat units of approximately 360 bp. In addition, CA88 also possesses an internal CA microsatellite, identified as SmBr18. Both PCR and BLAST analysis have been used to analyse and ...

Introduction: The responsibility of Schistosoma mansoni in female infertility is still controversial. This study was conducted to evaluate the effect of acute and chronic schistosomiasis mansoni infection on the endometrium using immunohistochemical analysis of uterine hormone receptor expression. Methods: Twenty-four nonpregnant swiss albino mice were divided into three groups: control, noninf...

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Schistosoma mansoni cercariae were removed from clear and turbid water by flocculation with Sudanese bentonite clays, with Moringa oleifera seeds as well as with pure bentonite. The flocculation technique employed corresponds to that used to clarify Nile water in Sudanese villages. Moringa seeds, pure bentonite and one type of bentonite clay were able to reduce the number of cercariae by more t...

In this paper, nine geographical isolates of Schistosoma mansoni (three from Egypt, three from Saudi Arabia and 3 from Puerto Rico) were studied at the genotype level by RAPD analysis with two arbitrary primers. The genetic distance was measured by the percentage of unshared bands. The RAPD results showed that the Egyptian strains were closely related to Saudi strains but Puerto Rico strains cl...