■ ■ Reduced temperature dependence for decreasd on-column degradation IN T RO DU C T IO N While hydrophilic interaction chromatography (HILIC) has been widely used for separating small polar compounds, its application to large biomolecules, other than released glycans, has been surprisingly limited. In large part, this can be attributed to a paucity of suitable HILIC column technology and robus...
