Two alternatively spliced stem cell factor (SCF) transcripts encode protein products, which differ in the duration of membrane presentation. One form, soluble SCF (S-SCF) gets rapidly processed to yield predominantly secreted protein. The other form, membrane-associated SCF (MA-SCF) lacks the primary proteolytic cleavage site but is cleaved slowly from an alternate site, and thus represents a m...

conclusions the scf phenomenon is relatively frequent, particularly among patients with acute coronary syndrome who are scheduled for coronary angiography. hypertension, a low hdl-c level, and high hemoglobin level can be considered independent predictors of this phenomenon. results among the 3600 patients scheduled for selective coronary angiography, 75 (2%) met the scf criteria. scf and neca ...

Tubular KT-joints are quite common in offshore structural design and despite the crucial role of stress concentration factors (SCFs) in evaluating the fatigue performance of tubular joints. However, the SCF distribution in internally ring-stiffened KT-joints have not been investigated and no design equation is currently available to determine the SCFs for this type of joint. In the present pape...

DOI: 10.1002/elps.202200182 The cover picture shows the electrophoretic separation of amphetamine and cathinone derivatives, commonly known as new psychoactive substances (NPS), by use cyclofructan-based chiral selectors (CF-based CSs). In particular, a capillary electrophoresis column is demonstrated that filled with CS sulphated CF-7 (SCF-7). Both SCF-based CSs, SCF-6 SCF-7, exhibited remarka...

stem cell factor (scf) is a critical protein with key roles in the cell such as hematopoiesis, gametogenesis and melanogenesis. in the present study a comparative analysis on nucleotide sequences of scf was performed in humanoids using bioinformatics tools including ncbi-blast, mega6, and jbrowse. our analysis of nucleotide sequences to find closely evolved organisms with high similarity by ncb...

Stem cell factor (SCF) and hypoxia-inducible factor-1α (HIF-1α) both have important functions in pancreatic ductal adenocarcinoma (PDAC). This study aims to analyze the expression and clinicopathological significance of SCF and HIF-1α in PDAC specimens and explore the molecular mechanism at PDAC cells in vitro and in vivo. We showed that the expression of SCF was significantly correlated with H...

Stem cell factor (SCF) is a major mast cell growth factor that promotes differentiation and chemotaxis of mast cells and inhibits their apoptosis. SCF therefore may be involved in diseases associated with an increased number of tissue mast cells such as asthma, for which the major treatment is glucocorticoids. In this study, we evaluated the effect of the glucocorticoid budesonide on the consti...

introduction:patients with the coronary slow flow phenomenon (scf) frequently experience angina episodes. the purpose of this study was to determine efficacy of nicorandil in myocardial perfusion in patients with scf. methods: twenty patients (50.85 ± 12.96 y) with scf were studied.  we evaluate coronary slow flow according to protracted thrombolysis in myocardial infarction (timi) frame count....