This paper introduces a novel type of injectable temperature-sensitive chitosan polymer based in situ gel for the local delivery of Satranidazole into the infected periodontal pocket. The thermo gelling polymer, chitosan with different concentrations has been used for formulation of in situ gel of Satranidazole with 10 % propylene glycol as plasticizer and was allowed to cross linked with 1 % s...

Colon targeted delivery of satranidazole (STZ), which immediately releases the drug as soon as the drug delivery system reaches the colon was formulated. Different grades of pectin were used as a compression coat and the effect of degree of esterification (DE) of pectin on swelling and drug release property was evaluated. STZ is a sparingly soluble drug, so to obtain maximum effect of drug at t...