abstract        background and objective: staphylococcus aureus is the most common and important infectious agent. this bacterium can enter the bloodstream and cause some complications in the intensive care unit (icu).this organism can frequently be found in the nose and transmitted by the carriers. this study aimed to determine the efficiency of eradicating s. aureus from the nose of icu perso...

Intravascular infection due to Staphylococcus aureus requires colonization of subendothelium in the presence of shear forces. von Willebrand factor (VWF) is a large multimeric glycoprotein playing a key role in platelet adhesion to subendothelium. To determine whether VWF may also play a role in adhesion of S. aureus to endovascular sites, binding of VWF to S. aureus and adhesion of S. aureus t...

tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...

We report the complete genome sequence of the methicillin-sensitive Staphylococcus aureus (MSSA) strain FDA209P (ATCC 6538P and NCTC 7447).

S. aureus ID (bioMérieux, La Balme Les Grottes, France) is a new chromogenic agar medium designed to enable the isolation of staphylococci and the specific identification of Staphylococcus aureus. S. aureus produces green colonies on this medium due to production of alpha-glucosidase. To evaluate this medium, a total of 350 wound swabs were cultured onto S. aureus ID, CHROMagar Staph. aureus, a...

BACKGROUND Staphylococcus aureus alpha-toxin is a major virulence factor, but its mechanism of action in vivo is incompletely understood. METHODS We examined the role of alpha-toxin in S. aureus pneumonia using the mouse model of intranasal lung infection with S. aureus strain 8325-4 (hla(+) S. aureus) and an alpha-toxin-deficient mutant strain made on the 8325-4 background (hla(-) S. aureus)...

Chronic and recurrent bone infections occur frequently but have not been explained. Staphylococcus aureus (S. aureus) is often found among chronic and recurrent infections and may be responsible for such infections. One possible reason is that S. aureus can internalize and survive within host cells and by doing so, S. aureus can evade both host defense mechanisms and most conventional antibioti...

Tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. It has broad spectrum activity, including Staphylococcus aureus infections. This is the first study that evaluated the activity of Tigecycline against Staphylococcus aureus isolated from biological samples in Iran. In vitro activity of tigecycline against 160 Staphylococcus aureus including 99 methicil...

conclusions we report a high methicillin-resistant s. aureus rate in our hospital. additionally, t030 and t037 were the predominant spa-types among hospital-associated s. aureus. our findings emphasize the need for continuous surveillance to prevent the dissemination of multidrug resistance among different s. aureus protein a types in iran. background the incidence of nosocomial staphylococcus ...

background quorum sensing is a microbial cell-to-cell communication process. quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. gram-positive and gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. objectives the goal of this study was to assess the impact of subinhibitory concen...