statement of problem: amalgam is the most widely used dental restorative material. however, because of continuous low-level release of mercury from amalgam fillings, its safety has been questionable. purpose: the aim of this study was the evaluation of concentration of mercury in saliva before and after amalgam fillings and its relation with numbers and surfaces of amalgam fillings. materials a...

Methods: The prevalence of multiple sclerosis (MS) is high in patients suffering from 25-hydroxyvitamin D3 [25(OH)D] deficiency. The aim of this study was to investigate the possible association of saliva and serum 25(OH)D concentrations with MS in women.Methods: Serum and saliva 25(OH)D levels of 30 MS women and 30 matched healthy controls in this case-control study were measured by ELIS...

We describe a direct radioimmunoassay for cortisol in 10-microliter volumes of parotid saliva or whole saliva. Binding proteins are absent from these fluids, as demonstrated by the excellent correlation between results for samples assayed directly and by a comparison procedure involving extraction with 1,2-dichloroethane. The direct assay is specific, precise, and had a lower limit of sensitivi...

the aim of this study was to investigate the rheological behavior and mucoadhesive nature of saliva substitutes, by incorporating various mucoadhesive polymers into an artificial saliva pump spray formulation. for this purpose various mucoadhesive polymers including cellulosic polymers in the range of 0.1-1.0% and carbomers such as c974p, c971, c934p and c971 in the range of 0.01-0.1% were adde...

BACKGROUND Saliva tests that detect antibodies are used to diagnose HIV infection. The goal of this study was to determine whether saliva could be used for nucleic acid-based tests to measure HIV-1 virus load (VL) and detect drug resistance. METHODS 69 HIV infected individuals provided 5-10 ml of saliva and blood samples. Viral RNA was isolated from saliva and dried blood spots using the Nucl...

BACKGROUND Allergy to dog (Canis familiaris) is a worldwide common cause of asthma and allergic rhinitis. However, dander extract in routine diagnostics is not an optimal predictor of IgE-mediated dog allergy. Our objective was to evaluate saliva as an allergen source for improved diagnostics of allergy to dog. METHODS IgE-binding proteins in dog saliva and dander extract were analysed by imm...

Measurement of biological markers that demonstrate distinguishable and regular changes from preto postdialysis states can enable necessary monitoring of dialysis efficacy and the level of renal function in patients with end-stage renal disease. In a report in this issue of Clinical Chemistry, Blicharz et al. (1 ) suggest that the measurement of biomarkers in saliva may be an effective alternati...