نتایج جستجو برای: saffron toxicity

تعداد نتایج: 119541  

Journal: :مجله میکروب شناسی پزشکی ایران 0
ناهید رحیمی فرد nahid rahimi fard food and drug laboratory research center and department of food and drug control laboratory, ministry of health and medical education, tehran, iran1) مرکز تحقیقات آزمایشگاهی غذا و دارو و اداره کل آزمایشگاه های کنترل غذا و دارو، وزارت بهداشت، درمان و آموزش پزشکی هما حاجی مهدی پور homa haji mahdipour research center for traditional medicine, shahid beheshti university of medical sciences, tehran, iran.2) مرکز تحقیقات طب سنتی و مفردات پزشکی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران. محمد حسین هدایتی mohhamad hosein hedayati quality control department, pasteur institute of iran3) واحد کنترل کیفیت، انستیتو پاستور ایران سید محسن اسماعیلی mohsen esmaili microbiology department, unit of pharmaceutical sciences, islamic azad university, tehran4) گروه میکرب شناسی، واحد علوم دارویی، دانشگاه آزاد اسلامی، تهران

background and objective: in addition to the use of chemicals in food, pharmaceutical, cosmetic and hygiene industries, use of herbal and natural compounds have also increased. it seems natural ingredients compared with the chemical components show less side effects, such as mutagenicity and carcinogenesis however, their use can also be associated with side effects and toxicity. some significan...

Journal: :jundishapur journal of natural pharmaceutical products 0
toktam ziaee department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran bibi marjan razavi targeted drug delivery research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran hossein hosseinzadeh pharmaceutical research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran; pharmaceutical research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran, tel.: +98-5118819042, fax: +98-5118823251

conclusions: the co-administration of saffron aqueous extract and safranal reduced toxic effects of safranal in acute and sub-acute toxicities. background: saffron and its constituents are widely used around the world as a spice and medicinal plant. different constituents in medicinal herbs are thought to have the potential to induce useful and/or adverse effects. so, efforts have been made to ...

2010
Evropi Botsoglou Alexandros Govaris Ilias Giannenas Nickolaos Botsoglou

From ancient times, saffron, the flower of the plant Crocus sativus L., is widely used as a traditional medicine to promote health and fight disease. Crocus sativus is cultivated in different parts of the world such as Greece, Spain and, mainly, Iran. In view of its wide range of medicinal uses, saffron has submitted to extensive phytochemical and biochemical studies and a variety of biological...

Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. Additionally, other lines of studies have found toxicological effects of saffron.  Ho...

Journal: :modares journal of medical sciences: pathobiology 2014
fatemeh taheri s. zahra bathaie mahboobe ashrafi elham ghasemi

objective: crocin, the carotenoid isolated from saffron, has numerous medicinal properties which include anticancer and antioxidant activities. some antioxidants, such as carotenoids, can act as pro-oxidants at higher dosages and therefore induce tissue damage. in this situation antioxidant defense systems in the liver activate to prevent tissue damage. this study investigates the possible toxi...

طیرانی نجاران, زهرا, موسوی, سید هادی, پارسایی, حیدر,

Background and Objective: Diabetic neuropathy is one of the most frequent complications of diabetes. Despite some studies, the exact mechanism of glucose neurotoxicity has not been fully elucidated. Increased reactive oxygen species (ROS) has been proposed as a possible mechanism. Crocus sativus L. (saffron) has been known as a source of antioxidants. Therefore, neuroprotective effect of saffro...

2010
Daniele Naviglio Stefano Conti Lydia Ferrara Antonello Santini

Saffron is a spice obtained from the dried stigmas of the purple-flowered saffron crocus (Crocus sativus L.). The determination of the water content in saffron is very important in order to establish its microbiological stability and consequently to determine the commercial value. The average moisture content in dried saffron powder ranges between 10-12% causing a slow degradation of the produc...

Journal: :Saudi medical journal 2010
Ali A Shati Saad A Alamri

OBJECTIVE To study the biochemical and molecular hepatotoxicity induced by aluminium chloride (AlCl3) and the protective role of saffron and honey against such toxicity. METHODS This study was performed in the Department of Biology, College of Science, King Khalid University, Abha, Kingdom of Saudi Arabia between July and August 2009. Two mice strains, BALB/c and C57BL/6 (20 animals from each...

2010
Shiva Golmohammadzadeh Mahmoud Reza Jaafari Hossein Hosseinzadeh

The objective of this study was to investigate the effects of saffron as a natural sunscreen and moisturizer. The pollens of the saffron were dried and powdered in a grinder. The experimental formulations included a homosalate (8%) lotion reference, lotions with 2, 4 and 8% of grinded saffron, and the control lotion base without saffron. The lotions containing saffron were prepared like homosal...

2014
Reza AMIRNIA Mahdi BAYAT Mahdi TAJBAKHSH MAHDI BAYAT

To develop saffron planting in Urmia, West Azerbaijan, Iran, a split-split plot experiment based on CRBD was carried out in the Urmia University's research farm for two years (2013-14). Nanofertilizers (Fe, P, K and nofertilizer (control)) as main plots, saffron ecotypes (Mashhad, Torbat-Heydarieh, Torbat-jam, Gonabad, Ghaen and Birjand) as subplots and maternal corm weight (6, 8, 10 and 12 g) ...

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