In this study, optimization of production parameters influencing melanin production in an economical fruit waste extract was attempted using a garden soil isolate (Bacillus safensis). Taguchi approach was adopted for screening of critical parameters and further optimization was done using a central composite design of response surface methodology (RSM). At optimum conditions (pH 6.84 and Temp 3...

Background. While significant attention has been paid to the potential risk of pathogenic microbes aboard crewed spacecraft, the non-pathogenic microbes in these habitats have received less consideration. Preliminary work has demonstrated that the interior of the International Space Station (ISS) has a microbial community resembling those of built environments on Earth. Here we report the resul...

AIMS To identify the diversity of pigmented aerobic spore formers found in the environment and to characterize the chemical nature of this pigmentation. MATERIALS AND RESULTS Sampling of heat-resistant bacterial counts from soil, sea water and the human gastrointestinal tract. Phylogenetic profiling using analysis of 16S rRNA sequences to define species. Pigment profiling using high-performan...

Bacillus spp. are well known to protect plants from seed or soil-borne pathogens by the synthesis of various metabolites with antimicrobial activity, such as hy?drolytic enzymes and antibiotics. This study aimed select most effective a group ten antagonistic strains antifungal activity assay. were primarily isolated soil identified B. safensis, pumilus subtilis 16S rDNA sequencing. The four ana...

Efficiency of cellulase-free xylanases is one of the determining factors in paper and pulp industries. Use of microbes which can produce cellulase-free xylanases may help to overcome the current challenges in kraft pulp processing. Isolation and screening of microorganisms from local samples offers a possibility for obtaining the potential microbes for this purpose. This research was therefore ...

Bacteria closely related to Bacillus pumilus cannot be distinguished from such other species as B. safensis, B. stratosphericus, B. altitudinis and B. aerophilus simply by 16S rRNA gene sequence. In this report, 76 marine strains were subjected to phylogenetic analysis based on 7 housekeeping genes to understand the phylogeny and biogeography in comparison with other origins. A phylogenetic tre...

Bacteria interact with each other in nature and often compete for limited nutrient and space resources. However, it is largely unknown whether and how bacteria also interact with human fungal pathogens naturally found in the environment. Here, we identified a soil bacterium, Bacillus safensis, which potently blocked several key Cryptococcus neoformans virulence factors, including formation of t...