5-aminosalicylic acid (5-asa) is currently prepared by electrochemical reduction of 5-nitrosalicylic acid (5-nsa) in acidic media. in this work, electrolytic reduction of 5-nsa in alkaline media is presented. reactionconditions and parameters such as anode and cathode electrodes, electrolyte type, reaction time, temperature,current, and the ph for isolation of product are investigated. the yiel...

objective : the purpose of this study was to determine the construct validity and reliability of the two forms of the persian version of the difficulties in emotion regulation scale (ders-6 & ders-5-revised) in a clinical sample. methods : the clinical sample consisted of 181 patients diagnosed with functional gi disorders (fgid) who referred to the digestive psychosomatic clinic in isfahan in ...

A m i t r a z, a n i ns e c t i c i d e /a ca ri c i de of the f o r m a m i d i n e p e st i c i d e s group, is a ? 2 a d r e n e r g i c ag on i st a nd of t he a m i d i ne c h e m i ca l f a m il y generally us e d to c o n t r ol animal e c top a r a s i t e s. Poisoning due to am i t r a z i s r a r e and character...

a l t h o u g h m o s t c o m p a n i e s s p e n d l e s s o n p r o d u c t d e s i g n, e x p e r i e n c e s h o w s t h a t, t h e s e c o m p a n i e s h a v e t o p a y h i g h e r c o s t s d u e t o p r o d u c t i o n p r o b l e m s o r l o s s o f m a r k e t. l i t e r a t u r e s t u d i e s s h o w t h a t t h e d e s i g n f o r s i x s i g m a i s a p o w e r f u l a p p r o a ...

interleukin-12 (il-12) is a key cytokine involved in regulating the balance between th1 and th2 cells by promoting th1 response. a reduced capacity to produce this cytokine could lead to aberrant th2 development. on the same aspect significant impact of il-12 on invariant natural killer t (inkt) cells was reported. therefore, we examined the serum levels of il-12 and the absolute number of peri...

o r g a n i z a t i o n s i n a s u p p l y c h a i n a r e i n d e p e n d e n t e n t i t i e s. a l t h o u g h a c o m p l e t e l y i n t e g r a t e d s o l u t i o n m a y r e s u l t i n o p t i m a l s y s t e m p e r f o r m a n c e, s u p p l y c h a i n m e m b e r s a r e i n t e r e s t e d i n o p t i m i z i n g t h e i r o w n o b j e c t i v e r a t h e r t h a n t h a t o f t...

g l o b a l c o m p e t i t i v e n e s s h a s r e c e n t l y b e c o m e a b i g c h a l l e n g e f o r m a n y c o m p a n i e s a r o u n d t h e w o r l d, w h i c h a r e f o r c e d t o s e e k l o w e r c o s t s a n d h i g h e r q u a l i t y f o r w h a t t h e y p r o d u c e. t h e p r o s p e r i t y o f m a n u f a c t u r i n g f i r m s d e p e n d s o n s e l e c t i n g a n...

in the long-term management of ulcerative colitis patients, repeat dosing maybe required. since 5-asa is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. the aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-asa deliver...

background: interleukin (il)-8 plays important roles in the recruitment and activation of immune cells during visceral leishmaniasis (vl). genetic variations in il-8 modulate the expression of il-8 protein and may be associated with vl. this study aimed to evaluate polymorphisms at the il-8 −251 position in vl patients. methods: this cross-sectional study was performed on three groups: leishman...