abstract   introduction: it is demonstrated that the degree of clinical improvement in   parkinson's disease (pd) achieved by deep brain stimulation (dbs) is largely dependent   on the accuracy of lead placement. in addition, individual variability in the   situation of subthalamic nucleus (stn) is responsible for spatial inter-individual   fluctuations of the real patient's target.  ...

after alzheimer disease, parkinson disease (pd) is considered the most common neurodegenerative disease. its prevalence is the same in all area but it is common in males than females. from every 100 persons who are above 60 years old, one of them has pd. also 5-10% of patients are less than 40 years old. this progressive neuroinflammation disease isn’t fatal. in 60% of cases is with depression....

a full investigation into the features extracted from voice signals of people with and without parkinson’s disease was performed. a total of 31 people with and without the disease participated in the data collection phase. their voice signals were recorded and processed. the relevant features were then extracted. a variety of feature selection methods have been utilized resulting in a good perf...

Background. Previous surveys have shown that motor deficits precede the classical motor symptoms seen in Parkinson’s disease (PD) and that physical exercise may have beneficial effects on PD. Objectives. Here, we evaluated the potential of voluntary exercise to improve motor deficit in experimentally-induced Parkinson’s disease (6-OHDA) rats. Methods. Forty adult Wistar rats were ...

After Alzheimer disease, Parkinson disease (PD) is considered the most common neurodegenerative disease. Its prevalence is the same in all area but it is common in males than females. From every 100 persons who are above 60 years old, one of them has PD. Also 5-10% of patients are less than 40 years old. This progressive neuroinflammation disease isn’t fatal. In 60% of cases is with depre...

Objective(s): 99mTc-TRODAT-1, which binds to the dopamine transporter, could be used to image the dopaminergic system in diagnosis of Parkinson’s disease (PD). PD can be classified into two groups: late onset Parkinson’s disease (LOPD) and early onset Parkinson’s disease (EOPD). In this study we tried to determine the TRODAT SPECT findings in EOPD as compared to LOPD.Methods: Fifteen patients w...

Introduction: Parkinson’s disease (PD) is the second most neurodegenerative disorder which is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Clinical symptoms do not appear until approximately 70% of dopaminergic neurons and 80% of the striatal dopaminergic terminals have been lost. Thus, detecting nonclinical factors such as detecting b...

while parkinson's disease (pd) has traditionally been defined by motor symptoms, many researches have indicated that mild cognitive impairment is common in non-demented pd patients. the purpose of this study was to compare verbal fluency performance in non-demented parkinson's disease patients with healthy controls.in this cross-sectional study thirty non-demented parkinson's disease patients a...

More than 10 million people worldwide are living with Parkinson’s disease (PD). The ages of people who have Parkinson are variable, usually between 50 and 80 years, the average of them is 55 years old. The symptoms of PD are progressive, and within 10 to 20. It happens when dopaminergic neurons were being degenerate. Peripheral and central inflammatory and oxidative stress pathways play a...

objective: parkinson's disease (pd) is one of the most common neurodegenerative disorders which is characterized by tremor, rigidity, bradykinesia and postural disturbances. studies indicate that grape juice and exercise may have beneficial effects on neurodegenerative disorders. therefore, in the present study, we evaluated the effects of red grape juice (gj) together with treadmill runni...