We investigated the role of singlet oxygen (generated from photoactivation of rose bengal) on the calcium transport and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum (SR). Isolated cardiac SR exposed to rose bengal (10 nM) irradiated at 560 nm resulted in significant inhibition of Ca2+ uptake (from 2.27 +/- 0.05 to 0.62 +/- 0.05 mumol Ca2+/mg.min [mean +/- SEM], p less than 0.01) and...

Rabbit corneal endothelial cells demonstrated an increase of endothelial membrane permeability to inulin following perfusion with 5 X 10(-6) M rose bengal and exposure to 1050 muW/cm2 incandescent light for either 1 min or 5 min when compared to corneas similarly perfused with rose bengal but not exposed to light. Endothelial permeability to dextran was unaltered following the photosensitizatio...

PURPOSE Rose bengal is an organic anionic dye used to assess damage of the ocular surface epithelium in ocular surface disease. It has been proposed that mucins have a protective role, preventing rose bengal staining of normal ocular surface epithelial cells. The current study was undertaken to evaluate rose bengal staining in a human corneal-limbal epithelial (HCLE) cell line known to produce ...

S FOR SCIENTIFIC PROGRAM: TO BE PRESENTED ORALLY ABSTRACTS FOR SCIENTIFIC PROGRAM: TO BE PRESENTED BY TITLE ONLY ABSTRACTS FOR TECHNOLOGISTS: SCIENTIFIC PROGRAM AUTHORS' INDEX SCIENTIFIC EXHIBITS COMMERCIAL EXHIBITS Thia On• Ill@Ill IIII @III@IIII III 11111 HI I G14A-X2P-TYPT 270

BACKGROUND The word "Cancer" itself is sufficient to cause a fear in the minds of people. Early detection of oral potentially malignant and malignant disorders is still a diagnostic challenge for most of the clinicians. In the present study, we have evaluated the efficacy of Rose Bengal staining in the detection of oral premalignant and malignant lesions. AIM The aim of the study was to evalu...

Rabbit corneal endothelial cells demonstrated an increase of endothelial membrane permeability to inulin following perfusion with 5 X 10~ M rose bengal and exposure to 1050 /txW/cm incandescent light for either 1 min or 5 min when compared to corneas similarly perfused with rose bengal but not exposed to light. Endothelial permeability to dextran was unaltered following the photosensitization r...

The objective of this study was to determine whether reactive oxygen intermediates (e.g., singlet oxygen and the superoxide radical) can rapidly induce electrophysiological disturbances leading to the genesis of arrhythmias, even in the absence of ischemia and reperfusion. Rat hearts (n = 6 per group) were perfused aerobically at 37 degrees C for 10 minutes without rose bengal and for 5 minutes...

The authors have studied the influence of rose bengal, and, by comparison, of uranin, on choleresis in the rabbit. Uranin induced an increase in bile flow and a decrease in bile salt concentration in bile. These results are consistent with an osmotic mechanism, as proposed by Sperber (1959). By contrast, rose bengal induced a marked decrease in bile flow and an increase in bile salt concentrati...

the use of colored semiconductor oxide like copper (ii) oxide and nickel (ii) oxide for photocatalytic bleaching of rose bengal was investigated in detail. in order to harness the solar energy, the effective wavelength of the photocatalyst is to be expanded into the visible region and that increases the rate of photocatalytic bleaching of the dye. progress of the reaction was observed spectroph...