Traditional methods of treatment of immature root with necrotic pulp and apical periodontitis pose multiple challenges. These challenges include disinfection of the root canal with standard protocols that aggressively use endodontic files, filling the root canal with an open apex that provides no barrier for stopping the root filling material before impinging on the periodontal tissues, and the...

The regeneration of the pulp-dentin complex has been a great challenge to both scientists and clinicians. Previous work has shown that the presence of prior infection may influence the characteristics of tissues formed in the root canal space after regenerative endodontic treatment. The formation of ectopic tissues such as periodontal ligament, bone, and cementum has been observed in the root c...

Complete debridement and thorough disinfection of infected root canals are considered mandatory for the success of root canal treatment. However, canal preparation and irrigation are not always effective in eliminating total microflora from the root canal system. Traditionally, calcium hydroxide has proven to be an excellent intracanal medicament for infected root canals. However, it is known t...

OBJECTIVES The present in vivo study was designed to assess the efficacy of 3 root canal disinfection protocols in immature dog teeth with apical periodontitis (AP). MATERIAL AND METHODS Forty immature premolars with pulp necrosis and AP of five Beagle dogs were used. Three experimental disinfection protocols were established. After irrigation with 40 ml 5.25% sodium hypochlorite using the En...

Root canal treatment of teeth presenting immature development is a great challenge for both the patient and the professional. The thinness of the root canal walls of immature teeth may lead to root fracture and thus the outcomes of such treatments are uncertain. Revascularization is based on root canal decontamination followed by the induction of blood migration from the periapical tissues and ...

Introduction: Primary root canal treatment success depends on a number of variables, including debridement and disinfection of the root canal system to remove all bacteria and diseased pulpal and dentinal tissues. Complex root canal anatomy, such as concealed isthmuses, apical deltas and lateral canals, hinder this objective, making instrumentation of these regions nearly impossible. Recent adv...

Due to limitations in standard endodontic therapy there have been great endeavors to effectively clean, shape and disinfect the root canal system while preserving the natural anatomy of the tooth [1]. Maintaining the natural canal anatomy and preservation of tooth structure has been correlated to higher clinical success rates [2-5]. A major issue in tooth preservation is the need to maximize cl...

Pulp canal obliteration is defined as a deposition of hard tissue within the root canal space. These tissues can eventually p roduce the radiographic appearance of a root canal space that has become partial or completely ca lcified. Success in root canal treatment is based on proper debridement, disinfection and obturation of the root canal system Calcified root canal causes problem during endo...

Aims Since the inception of the cleaning and shaping concept, the use of instruments and chemicals has remained as the central paradigm of the root canal therapy. However, cleaning and shaping the root canal space adequately is a well-known difficult task, particularly in root canal systems with intercanal connections, isthmuses, and fins. Recently, micro-computed tomography (micro-CT) technolo...