نتایج جستجو برای: rock

تعداد نتایج: 38846  

In this work, the effect of rock bolt angle on the shear behavior of Rock Bridges is investigated using the particle flow code in two dimensions (PFC2D) for three different Rock Bridge lengths. Firstly, the calibration of PF2D is performed to reproduce the gypsum sample. Then the numerical models with the dimensions of 100 mm * 100 mm are prepared. The Rock Bridge is created in the middle of th...

2012
Phillip H. Larson Ronald I. Dorn

No prior research has documented the different types of rock coatings in Yosemite Valley, despite the evident black streaks down Yosemite Falls, the light granitic rock exposed by recent rock falls contrasting with dark rock coatings, and the millions of visitors who have photographed the coated rocks of Yosemite. This paper identifies the types of rock coatings found on Half Dome, in Yosemite ...

2003
A. F. C. Haldemann M. P. Golombek

Introduction: We have completed analysis of a new near-field rock count at the Mars Pathfinder landing site and determined that the previously published [1,2] rock count suggesting 16 % cumulative fractional area (CFA) covered by rocks is incorrect. The earlier value is not so much wrong (our new CFA is 20%), as right for the wrong reason: both the old and the new CFA’s are consistent with remo...

2016
Bao-zhu Tian Shan-jun Liu Yan-bo Zhang Zhan-le Wang

Original scientific paper Rock burst is a common serious geological hazard in underground engineering, which seriously affects the progress of projects. The mechanism of rock burst can be explained by the distribution law of rock fragments and its fractal characteristics. A simulation experiment of rock burst was conducted with the granite samples under a biaxial loading machine system to analy...

2015
Aurélie Alleaume-Butaux Simon Nicot Mathéa Pietri Anne Baudry Caroline Dakowski Philippe Tixador Hector Ardila-Osorio Anne-Marie Haeberlé Yannick Bailly Jean-Michel Peyrin Jean-Marie Launay Odile Kellermann Benoit Schneider Paul Lingor

In prion diseases, synapse dysfunction, axon retraction and loss of neuronal polarity precede neuronal death. The mechanisms driving such polarization defects, however, remain unclear. Here, we examined the contribution of RhoA-associated coiled-coil containing kinases (ROCK), key players in neuritogenesis, to prion diseases. We found that overactivation of ROCK signaling occurred in neuronal s...

2017
Chitharanjan Duvoor Vijaya S. Dendi Asween Marco Nawal S. Shekhawat Aditya Chada Rahul Ravilla Chaitanya K. Musham Wasique Mirza Arun Chaudhury

1 Department of Endocrinology and Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA, 2 GIM Foundation, Little Rock, AR, USA, 3 Department of Internal Medicine and Hospital Medicine, Christus Trinity Mother Frances Hospital, Tyler, TX, USA, 4 Department of Policy, University of Arkansas for Little Rock, Little Rock, AR, USA, 5 Tutwiler Clinic, Tutwiler, MS, USA...

2006
Sridevi Jade T. G. Sitharam

This paper deals with the statistical analysis of the uniaxial compressive strength and of the elastic modulus of jointed rock masses under different confining pressures. Properties of the rock masses with different joint fabric, with and without gouge have been considered in the analysis. A large amount of experimental data of jointed rock masses from the literature has been compiled and used ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده علوم 1392

سلول های بنیادی جنینی انسانی قابلیت های شگرفی در حوزه ی پزشکی و سلول درمانی دارند. در این راستا، منفرد کردن سلول های بنیادی انسانی با هدف گسترش سریع این سلول ها و انجام دست ورزی های مختلف بر روی آن ها اجتناب ناپذیر است. اما در این فرایند مانعی وجود دارد، بدین معنا که آپوپتوز القا شده در اثر فعالیت مسیر سیگنالی rho/rock که در نتیجه ی منفرد شدن سلول های بنیادی انسانی فعال می شود، کشت و دست ورزی ا...

2012
Manish K. Rana Rebecca A. Worthylake

Background: Negative regulatory mechanisms of ROCK signaling are poorly understood. We have discovered a novel mechanism to attenuate ROCK signaling. Results: Coronin1B is a novel binding partner of ROCK2 that inhibits ROCK signaling to myosin. Conclusion: Coronin1B regulates ROCK by a novel signal attenuation mechanism. Significance: Coronin1B attenuation of ROCK signaling is associated with N...

2017
Gangbing Song Weijie Li Bo Wang Siu Chun Michael Ho

Rock bolts have been widely used as rock reinforcing members in underground coal mine roadways and tunnels. Failures of rock bolts occur as a result of overloading, corrosion, seismic burst and bad grouting, leading to catastrophic economic and personnel losses. Monitoring the health condition of the rock bolts plays an important role in ensuring the safe operation of underground mines. This wo...

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