background: in this study we evaluated the incidence of hypothyroidism in patients who received external beam radiation due to cancer, when radiation portals included thyroid gland. methods: this prospective study was conducted from april 2004 to december 2005 among patients with head and neck or breast malignancies who referred to radiation oncology department of cancer institute, imam khomein...

BACKGROUND There are no specific recommendations for the management of breast cancer patients with germ-line p53 mutations, an exceptional genetic condition, particularly regarding postoperative radiotherapy. Preclinical data suggested that p53 mutations conferred enhanced radiosensitivity in vitro and in vivo and the few clinical observations showed that Li-Fraumeni families were at a higher r...

As we know breast cancer is the second death reason in Iran. One step of treatment process is radiotherapy, which needs careful consideration of contouring and therapeutic techniques Lung, thyroid, spinal cord, trachea and humerus are sensitive organs in breast cancer radiation therapy.  The most clinical studies recommended two ways for delivering 95 percent of dose to supraclavicular and ...

Introduction: Critical organs and structures may receive significant amounts of irradiation even if they are not the target of radiotherapy or located outside the treatment field. Although the sensitive thyroid gland and lens are not directly the targets of treatment, they can be affected by irradiation during the treatment of tumours in head and neck region. The purpose of thi...

background: we evaluated the efficacy of a simple belly-board device (bbd) designed and made in our department for reduction of small bowel inside the post-operative pelvic radiotherapy fields of rectal carcinomas. methods: a very simple bbd was designed and manufactured in our department. it was made of acrylic glass, and was 128 cm long, 40 cm wide, and 9 cm high, with a 25x25 cm square openi...

abstractwe are reporting a 43-year-old female breast cancer case with a solitary metastatic adenocarcinoma in clivus. this patient with a stage ii (t1n1m0) breast cancer history has been followed for 7 years.  modified radical mastectomy (mrm) and 6 courses chemotherapy with cmf (cyclophosphamide, metotrexate, 5fu) regimen were done for her at the time of diagnosis. also, she took tamoxifen twe...

Rates of thyroid cancer in women with a history of breast cancer are higher than expected. Similarly, rates of breast cancer in those with a history of thyroid cancer are increased. Explanations for these associations include detection bias, shared hormonal risk factors, treatment effect, and genetic susceptibility. With increasing numbers of breast and thyroid cancer survivors, clinicians shou...

Prostate cancer is the most common and second leading cause of death among men in the world. Nowadays, radiotherapy has been known as one of the most affecting methods for prostate cancer treatment. Nevertheless, radiotherapy is accompanied by the concern of developing secondary cancers by the scattered radiation to the neighbor  organs at risk. Several studies have shown that secondary cancers...

breast cancer is the most common cancer in women after skin cancer. in iran, the presentation age of this cancer is younger than the global average. there are different therapeutic methods for treatment of breast cancer and the choice of treatment depends on the stage of the disease as well as its type and characteristics. therapeutic methods include surgery, radiotherapy, and systemic therapie...

BACKGROUND Breast cancer is the most frequently diagnosed cancer and the leading global cause of cancer death among women worldwide. Radiotherapy plays a significant role in treatment of breast cancer and reduces locoregional recurrence and eventually improves survival. The treatment fields applied for breast cancer treatment include: tangential, axillary, supraclavicular and internal mammary f...