background: heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. we studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta thalassemia intermedia, and a control group. methods: eighty asymptomatic patients with thalassemia major and 22 asymptomatic cases with thalas...

Background: Cardiac dysfunction due to chronic anemia and hemosiderosis are the major causes of death among patients with thalassemia intermedia. This study was performed to compare the cardiac function in thalassemia intermedia patients with normal subjects by means of echocardiography. Materials and Methods: This was a case-control study performed on 22 patients affected by thalassemia int...

background: cardiac dysfunction due to chronic anemia and hemosiderosis are the major causes of death among patients with thalassemia intermedia. this study was performed to compare the cardiac function in thalassemia intermedia patients with normal subjects by means of echocardiography. materials and methods: this was a case-control study performed on 22 patients affected by thalassemia interm...

OBJECTIVE In patients with repaired tetralogy of Fallot, to examine (1) a possible relation between right ventricular enlargement and QRS prolongation, and (2) the effect of right ventricular enlargement caused by pulmonary regurgitation on the right ventricular ejection fraction, evaluated by three dimensional echocardiography, and global function, evaluated by the myocardial performance index...

doppler-derived myocardial performance index (mpi), defined as the sum of isovolumetric contraction and relaxation durations divided by ejection time, is an easily measured and reproducible index that shows both systolic and diastolic myocardial function. the goal of this study was to define normal values of right ventricular (rv) mpi in neonates in the first 48 to 72 hours of life. fifty-one q...

OBJECTIVE Despite progresses in surgical correction of Tetralogy of Fallot, pulmonary insufficiency and progressive dysfunction of the right ventricle impress its long-term prognosis. In this study we examined the correlations between QRS duration, pulmonary insufficiency and right ventricular performance index. METHODS We enrolled 57 repaired Tetralogy of Fallot patients. QRS duration on ele...

background: there is some evidence indicating improvement in myocardial performance after atrial septal defect closure, either device closure or surgical, but ventricular dyssynchrony has not been evaluated before and after surgical closure. the aim of this study was to evaluate ventricular mechanical dyssynchrony in patients with atrial septal defect before and after surgical closure. methods:...

background: sickle-cell disease (scd) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. cardiovascular events and complications are the leading cause of mortality and morbidity in patients with scd. tissue doppler imaging and the myocardial performance index (tei index), are simple indices for the assessment of the cardiac f...