نتایج جستجو برای: response biomarkers

تعداد نتایج: 1062288  

ژورنال: کومش 2022

Precision medicine, the selection of treatment based on the genetic characteristics of patients, is one of the new paradigms of medical science. Using genetic characteristics and biomarkers, patients' response to different treatments is evaluated and finally, a specific one is selected for them. In other words, using genetic information or biomarkers, the safety, effectiveness and outcomes of t...

Gholamreza Rahbari Banaeian Nemat Bilan, Sina Pakdel, Sina Raeisi

Background Making decision on asthma as an inflammatory disease is done mostly on the airways function and the patient symptoms which most of them are nonspecific and subjective. Also, the children are not able to express their signs and collaboration in examination of the lungs function. Evaluation of serum level inflammatory biomarkers can be useful in assessment of the response to treatment ...

Background: This study was aimed to evaluate the effects of physical exercise on bone mineral density (BMD), lean body mass (LBM) and bone biomarkers in children with acute lymphoblastic leukemia on chemotherapy. Methods: forty-six leukemic children were randomly assigned to two groups; exercise group (E) undergoing supervised mixed exercise program consisting of aerobic, resistance and flexib...

2010
Andrew F. Leuchter Ian A. Cook Steven P. Hamilton Katherine L. Narr Arthur Toga Aimee M. Hunter Kym Faull Julian Whitelegge Anne M. Andrews Joseph Loo Baldwin Way Stanley F. Nelson Steven Horvath Barry D. Lebowitz

During the past several years, we have achieved a deeper understanding of the etiology/pathophysiology of major depressive disorder (MDD). However, this improved understanding has not translated to improved treatment outcome. Treatment often results in symptomatic improvement, but not full recovery. Clinical approaches are largely trial-and-error, and when the first treatment does not result in...

Journal: :Journal of renal endocrinology 2023

Biomarkers are molecules that can be measured in the body and reflect disease activity or progression. They used to diagnose monitor disease, predict treatment response, identify potential therapeutic targets. Several types of biomarkers have been studied context IgA nephropathy, including protein, gene expression, epigenetic, microRNA biomarkers. improve accuracy specificity diagnosis nephropa...

2013
Wolfgang Sadee

Pharmacogenomic biomarkers can optimize an individual’s therapy; however, the overall role of genetic factors in drug response remains uncertain. The majority of genetic variants currently used as clinical pharmacogenomic biomarkers affect drug metabolism and transport, while fewer biomarkers accurately predict drug response (pharmacodynamics). This article evaluates heritable aspects of drug t...

2006
C. Eric Hack Lynne T. Haber Andrew Maier Paul Schulte Bruce A. Fowler W. Gregory Russell E. Savage

To facilitate the use of biomarkers in human health risk assessments, a biomarker decision support system is presented that systematically identifies, documents, validates, and incorporates biomarkers into occupational risk assessments. A biomarker database structure was developed and decision rules were identified to organize the diverse types of data to support an occupational risk assessment...

Journal: :iranian journal of veterinary medicine 2013
mehrdad pourjafar aliasghar chalmeh khalil badiei saeid nazifi samaneh keshavarz

background: information regarding serum biochemicalprofile can reflect cardiovascular performance in animals.although studies have evaluated the inter-relationship amongcardiovascular biomarkers in animals and human beings, thereare no reports of such a probable relationship in camelids.objectives: the aim of the present study was to provide dataon the correlations among cardiovascular biomarke...

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