نتایج جستجو برای: responder
تعداد نتایج: 6489 فیلتر نتایج به سال:
Understanding the genetic mechanisms of sensitivity to targeted anticancer therapies may improve patient selection, response to therapy, and rational treatment designs. One approach to increase this understanding involves detailed studies of exceptional responders: rare patients with unexpected exquisite sensitivity or durable responses to therapy. We identified an exceptional responder in a ph...
سابقه و هدف: کارکنان بهداشتی، درمانی همواره در معرض خطر ابتلا به هپاتیت Bمیباشند. این مطالعه با هدف تعیین سطح سرمی آنتـــــیبادی Anti HBs در پرسنل درمانی واکسینه شده علیه هپاتیت B و تأثیر فاکتورهای مؤثر برآن انجام گرفت.مواد و روشها: مطالعه به روش توصیفی روی 128 نفر از پرسنل درمانی بیمارستان شهید بهشتی کاشان که همگی به طور کامل علیه هپاتیت B واکسینه شده بودند، در سال 1381، انجام گرفت. از افراد ...
previous studies had shown that sub-inhibitory concentrations of silver sulphadiazine (agsd) stimulated the production of toxic shock syndrome toxin-1 in certain strains (responder strains) of staphylococcus aureus and that protease production was also affected. no changes were detected in other strains (non-responders). extracellular proteins from eleven responder and non-responder strains gro...
SUMMARY In this issue of Cancer Discovery, AI-Ahmadie and colleagues identify a somatic mutation in the RAD50 gene as a likely contributing factor to an unusual curative response to systemic combination therapy employing the DNA-damaging agent irinotecan and a checkpoint kinase 1 inhibitor in a patient with recurrent, metastatic small-cell cancer. This study highlights the importance of in-dept...
The cellular requirements for immune response (Ir) gene expression in a T cell proliferative response under dual Ir gene control were examined with radiation-induced bone marrow chimeras. The response to poly(Glu55Lys36Phe9)n (GLphi) requires two responder alleles that in the [B10.A X B10.A(18R)]F1 map in I-Ab and I-Ek/Cd. Chimeras in which a mixture of the nonresponder B10.A parental cells (wh...
It has previously been demonstrated that gingival fibroblasts derived from nifedipine-reactive patients (nifedipine responders) show a greater cell proliferation rate than those from nifedipine non-reactive patients (nifedipine non-responders) in the presence of 1 microM nifedipine. The aim of the present study was to characterize cell cycle differences between nifedipine responder and non-resp...
background to treat viral infection of chronic hepatitis c (chc) is a main strategy to prevent progression of liver disease, and cancer. some patients with chc have failed to respond to the common antiviral therapy in different populations. objectives in the current study it was aimed to find out the possible role of multiple drug resistance gene1 (mdr1) in non-responder patients with chc infec...
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