Our laboratory is engaged in an ongoing analysis of a 103-compound data set containing reliable intravenous pharmacokinetic parameters in the rat, dog, monkey, and human, and we have previously reported our findings regarding extrapolation of clearance. In this article, we report on our findings regarding volume of distribution and mean residence time. Various allometric and nonallometric metho...

Sequences of residence times (RTs) associated with the escape from metastable states are observed in many fields. Here we study analytically and numerically the correlations among RTs for a bistable stochastic system driven by dichotomous noise. Our theory predicts an oscillatory behavior of the correlations with respect to the lag between RTs. Correlations vanish at all lags if the switching r...

The authors examined the association between perceived safety of neighborhood and likelihood of exercise among adult residents of eight European cities. Data were collected by a survey of neighborhood, housing, and health conducted by the World Health Organization in 2002 and 2003. Baseline category logistic regression models were fit to estimate the association between perceived safety and exe...

As the most basic cloud service model, Infrastructure as a Service (IaaS) has been widely used for serving the evergrowing computing demand due to the prevalence of the cloud. Using pools of hypervisors within the cloud, IaaS can support a large number of Virtual Machines (VMs) and scale services in a highly dynamic manner. However, it is well-known that the VMs in IaaS are vulnerable to co-res...

Migration as a human phenomenon has some consequences and repercussions. One of these effects is crime commitment and inducing disturbance in land and national security in immigrants' residence country, in other word, international migration, especially illegal migration, have different penal-security effects. Finding reason that the permeability of borders and increasing illegal traffic, drug ...

A large number of aged Americans depend on Social Security benefits to stay out of poverty. Those who have very small Social Security checks, or who have none at all, rely heavily on the Supplemental Security Income (SSI) program for much of their income. Most aged SSI recipients have earnings histories to explain their lack of adequate Social Security benefits. Information on these histories w...

Dinshaw Mistry is a doctoral candidate in Political Science at the University of Illinois, Urbana-Champaign, and is currently in residence at the Brookings Institution, Washington, D.C. He has recently published articles on the Indian space program (Pacific Affairs) and the missile nonproliferation regime (Contemporary Security Policy). DOMESTIC-INTERNATIONAL LINKAGES: INDIA AND THE COMPREHENSI...

The residence time of a single dye molecule diffusing within a laser spot is propotional to the total number of photons emitted by it. With this application in mind, we solve the spherically symmetric "residence time equation" (RTE) to obtain the solution for the Laplace transform of the mean residence time (MRT) within a d-dimensional ball, as a function of the initial location of the particle...

The Supplemental Security Income (SSI) program, established by the Social Security Amendments of 1972 (Public Law 92-603), was designed to provide cash assistance to needy aged, blind, and disabled citizens, and noncitizens lawfully admitted for permanent residence or permanently residing under color of law. Since then, this means-tested program has undergone many legislative changes that affec...