Natural products provide excellent potential leads for drug development because of their chemical diversity and biological functionality. However, the productivity of discovery of new, pharmacologically active natural products has traditionally been low due to inherent difficulties and costs associated with extract dereplication, i.e., isolation, purification and structure elucidation of indivi...

What is the future of music and music-related technology? In this lecture, I argue that cultural and technological changes are ultimately shaped by human emotions. These emotions, in turn, reflect underlying values that arose from evolutionary-adaptive goals. Values such as friendship, social status, cultural identity, security, health, humor, novelty, engagement, etc. are concretely manifested...

This paper reviews methodological innovation in qualitative research. It comprises a narrative review of 57 papers published between 2000-2009 in which claims to innovation in qualitative methods have been made. These papers encompass creative methods, narrative methods, mixed methods, online/e-research methods and software tools. The majority of claims of innovation are made for new methods or...

The Virtual Observatory (VO) for Astronomy is a framework that empowers astronomical research by providing standard methods to find, access, and utilize astronomical data archives distributed around the world. VO projects in the world have been strenuously developing VO software tools and/or portal systems. Interoperability among VO projects has been achieved with the VO standard protocols defi...

Snip is a tool that allows a user to constrict the view onto any window. We report on a controlled study of the snip tool in the context of a multiple-monitor environment. The study was designed based on observed user behavior in a field study of multiple-monitor users’ snipping habits. Analysis provided results that indicate that users can expect to reference information approximately 15% to 3...

Communities of Practice make intensive use of information and communication technologies (ICT) to meet their needs of interaction among their members. At present, the main supporting tool for these communities is the Internet and the software tools available for their users. With the advent of digital TV, however, new resources have become available to these interactive communities. This study ...

With the sudden passing of P. Michael Conn, the Endocrine Society lost one of the hardestworking scientists we have known. Michael was born in Oil City, Pennsylvania, received his BS from the University of Michigan, his MS from North Carolina State University, and his PhD from Baylor College of Medicine (working in Bert O’Malley’s laboratory). Following a postdoctoral fellowship in the Dufau-Ca...