Background Infertility is a major problem with a prevalence around 9% in the world and a life time prevalence of about 25% in Iran. Assisted reproductive technique (ART), came into the world on 1978 with the birth of Luise Brown, but early days of ART in Iran was not clear. The aim of this study is to investigate the history of ART in Iran and its time line in this Islamic society. MaterialsAnd...

Background Infertility may have many emotional and psychological implications on infertile couples. So far, different methods for reducing anxiety in infertile couples have been evaluated. The goal of this study is to evaluate the effect of provision of information regarding infertility treatment to infertile couples on their anxiety levels. MaterialsAndMethods This study was conducted as a bef...

Background: Advances in medical technology have had major impacts on human reproduction. The development of effective contraceptive methods has reduced unwanted fertility, and the development of a variety of drugs and procedures has, for the first time, permitted women with fertility problems to reasonably expect that they can fulfill their desires to have children. So, The aim of this review a...

Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...

hla-g is a tolerogenic molecule that expresses in cytotrophoblast cells and plays an important role in immune response suppression in maternal decidua. interactions between the extracellular domains of the hla-g protein with cell receptors of the immune system are well-known.this  study  investigated  the  association  between  hla-g  gene  polymorphism  with repeated implantation failure (rif)...