The reproducibility of an experimental result is a fundamental assumption in science. Yet, results that are merely confirmatory of previous findings are given low priority and can be difficult to publish. Furthermore, the complex and chaotic nature of biological systems imposes limitations on the replicability of scientific experiments. This essay explores the importance and limits of reproduci...

Advances in computing technology have spurred two extraordinary phenomena science: large-scale and high-throughput data collection coupled with the creation implementation of complex statistical algorithms for analysis. These brought about tremendous advances scientific discovery but raised serious concerns. The complexity modern analyses raises questions reproducibility analyses, meaning abili...