BACKGROUND The primary analysis in a longitudinal randomized controlled trial is sometimes a comparison of arms at a single time point. While a two-sample t-test is often used, missing data are common in longitudinal studies and decreases power by reducing sample size. Mixed models for repeated measures (MMRM) can test treatment effects at specific time points, have been shown to give unbiased ...

Discriminant analysis (DA) encompasses procedures for classifying observations into groups (i.e., predictive discriminative analysis) and describing the relative importance of variables for distinguishing amongst groups (i.e., descriptive discriminative analysis). In recent years, a number of developments have occurred in DA procedures for the analysis of data from repeated measures designs. Sp...

STUDY DESIGN This study is a repeated measures design to measure the lumbar spine response to typical school backpack loads in healthy children. The lumbar spine in this setting was measured for the first time by an upright magnetic resonance imaging (MRI) scanner. OBJECTIVE The purpose of this study is to measure the lumbar spine response to typical school backpack loads in healthy children....

Early fatigue and rutting are among the most common types of road damage due to their main relationship with pavement performance. These damages occur excessive loads on axles vehicles or improper design mixture in addition traditional methods used paving designs. Therefore, these premature must be avoided for proper performance service road. In order overcome some weaknesses, mechanical-empiri...