STUDY QUESTION What is the prevalence of chronic endometritis (CE) in women with repeated unexplained implantation failure (RIF) at IVF, and how does antibiotic treatment affect the reproductive outcome? SUMMARY ANSWER Chronic endometritis, associated with infection with common bacteria or mycoplasma, is common in women complaining of RIF and antibiotic treatment significantly improves the re...

PGD (preimplantation genetic diagnosis) of aneuploidy for chromosomes X, Y, 13, 18 and 21 was carried out on 196 embryos from 36 infertile patients classified with a poor prognosis due to (i) maternal age, (ii) repeated in-vitro fertilization (IVF) failures and (iii) mosaic karyotype. The percentage of abnormal embryos was comparable in the three groups of patients: maternal age 63%, repeated I...

This is the first report implementing combined density gradient centrifugation/Zeta (DGC/Zeta) sperm selection procedure for a couple with eleven previous intra cytoplasmic sperm injection/ in vitro fertilization (ICSI/IVF) failure cycles. Semen analysis was carried out according to World Health Organization criteria. Protamine deficiency, DNA fragmentation and morphology were assessed by chrom...

background: recurrent spontaneous abortion (rsa) and in vitro fertilization (ivf) failure with unknown causes are the controversial issues that are probably related to the immune system. objective: to compare circulating nk cells expressing activation and inhibition surface markers between patients with rsa and ivf failure with those of healthy multiparous and successful ivf control women, resp...

ObjectiveTo identify predictor microRNAs (miRNAs) from patients with repeated implantation failure (RIF).DesignSystemic analysis of miRNA profiles the endometrium undergoing in vitro fertilization (IVF).SettingUniversity research institute, private IVF center, and molecular testing laboratory.Patient(s)Twenty five infertile discovery cohort 11 validation cohort.Interventions(s)None.Main Outcome...

A prospective cohort study has been performed to find out if the administration of an oxytocin antagonist (Atosiban) at the occasion of embryo transfer has an effect on the pregnancy rate in patients with repeated failure of implantation. A total of 52 women with repeated failure of implantation after IVF/ICSI were included in this study. The ongoing pregnancy rate (OPR) in the total group of p...

Recent evidence shows that through best standard operating procedures, chances of successful pregnancy and live birth delivery rates are less than 50%. Repeated Implantation Failure (RIF) following transfer of one or more numbers of cleavage or blastocyst stage embryos is the main cause of low pregnancy rate in IVF cycles; therefore, finding the causes and modifying treatment protocols to incre...

Objective Objective: The aim of this study was to investigate the effects of vaginal sildenafil on the outcome of patients with at least two times of unsuccessful IVF / ICSI. MaterialsAndMethods Method and Material(s): A total of 66 infertile women aged ≤ 38 years, with a history of normal ovarian reserve, two prior consecutive failed IVF/ICSI attempts, hCG day endometrial thickness