objective(s): the wide scale use of zinc oxide nanoparticles (zno nps) in the consumer market world makes human beings more prone to the exposure to zno nanoparticles and its adverse effects. therefore, the aim of the present study is to assess renal toxicity potential of zno and polyethylene glycol coated zno nanoparticles in rat.materials and methods: co-precipitation chemical method was used...

objective(s) portulaca oleracea l. is a herbaceous weed from portulacaceae family. it can be found in many parts of the world. modern pharmacological studies have demonstrated that p. oleracea have antioxidant effects. the protective effect of aqueous and ethanolic extract of p. oleracea against cisplatin-induced renal toxicity was studied in rats. materials and methods single intraperitoneal i...

Kidney is considered as the secondary target organ of nanoparticle (NP) toxicity. Since it primary excretion, NPs are expected to adversely affect renal system. Therefore, a comprehensive review recent knowledge on toxicity engineered nanoparticles (ENPs) was made. Mechanistic paradigms their have also been discussed.

Metallothioneins (MT) concentration, renal damage, and bone malformations were investigated in 38 adult Tursiops aduncus carcasses to determine any associations with cadmium, copper, zinc, mercury, lead and selenium. Significantly higher concentrations of cadmium, copper, and zinc in the liver were observed in dolphins showing evidence of more advanced renal damage. No significant differences i...

Aims and Objectives: Assessment of renal toxicity profile of 177Lu-DOTATATE based Peptide Receptor Radionuclide therapy (PRRT) in patients of Metastatic Neuroendocrine tumor (NET) with a single functioning kidney. Materials and Methods: This was a retrospective analysis of NET patients, who had undergone PRRT with 177Lu-DOTATATE at a large tertiary care centre. The patients selected for the stu...

Resveratrol, (3,5,4'-trihydoxystilbene) a compound found in grapes, mulberries, and peanuts, has antimycotic, antiviral, and beneficial cardiovascular and cancer preventive activities. It is being developed for several clinical indications. To evaluate the potential toxicity of resveratrol, rats were administered by gavage 0, 300, 1000, and 3000 mg trans-resveratrol per kilogram body weight per...

introduction: there have been many studies in recent years on the role of nitric oxide (no) in acute renal failure. in this study, the effects of inhibition or interoduction of no synthase on renal toxicity of gentamicin were investegated. materials & methods: isolated kidneys of male rats were perfused with tyrode buffer (t) as the control group, t+l-argrinine as group 2, t+l-name as group 3, ...