OBJECTIVES This study aimed to demonstrate if the addition of anti-inflammatory treatment to antibiotic therapy shows any superiority to the treatment with antibiotic only. METHODS Forty-nine Wistar rats were divided into 7 groups. Pyelonephritis was performed by E. coli injection to upper pole of kidneys except control group. Group 2 was not treated. Ceftriaxone, ketoprofen, "ceftriaxone + k...

Vesicoureteral reflex(VUR) is a common disease in children. Some studies indicated that the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism associated with the renal scar in VUR, but not all researchers agreed with it. To clarify the effect of ACE I/D polymorphism on renal scar risk in children with VUR, we performed the present meta-analysis. PubMed, CNKI, CBM, a...

background: diagnosis of kidney scar could prevent vesico urethral reflax and its complications such as hypertension and renal failure. this study was conducted to determine average kidney length and volume in infants by sonography to accurate diagnosis of scars. methods: this study was conducted on infants with the history of uti who referred to imam reza hospital, kermanshah iran, for dmsa sc...

BACKGROUND Acute pyelonephritis in children can leave a kidney scar that eventually can lead to hypertension or renal failure. 99mTc-dimercaptosuccinic acid renal scintigraphy (RC DMSA) is a widely accepted technique to assess children with acute pyelonephritis. AIM To evaluate the presence of residual kidney scars detected through RC DMSA, in children with a first episode of acute pyelonephr...

Urinary tract infection (UTI) is a common disease in childhood specially in female. In this study 50 patients with stablished diagnosis of UTI were evaluated by both renal scan with Tc-99m DMSA and renal sonography. The study revealed that most urinary tract infections are in children, Female sex between 5-9 years of age. Therefore the most important complications (Renal scarring) are als...

Introduction. Fibroblast growth factor 2 (FGF2) is a potent mitogenic factor of cortical fibroblasts and induces kidney fibrosis. We hypothesized that serum levels of FGF2 has an association with the severity of vesicoureteral reflux (VUR) and renal parenchymal scar. Materials and Methods. Between 2007 and 2009, a total of 28 children with VUR were enrolled in this study and were compared with ...

In their article entitled ‘Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin’, Chung and colleagues elegantly investigated the factors associated with severe cutaneous adverse reactions (SCAR) in patients taking allopurinol as antihyperuricaemic agent and found that impai...

Stellate scar sign is defined as the centrally-placed, welldefined, stellate area of low density on computed tomography (CT) appearance of solid tumors. This kind of radiating enhancement from the center of the tumor, which is also referred as “a spoke-wheel-like enhancement” or central scar sign, usually has been recognized as a specific finding of renal oncocytoma. We describe a patient who d...

PURPOSE To investigate and distinguish the computed tomography (CT) characteristics of chromophobe renal cell carcinoma (chRCC) and renal oncocytoma. MATERIALS AND METHODS Fifty-one patients with renal oncocytoma and 120 patients with chRCC, diagnosed by surgery between November 2005 and June 2015, were studied retrospectively. Two observers, who were urologists and unaware of the pathologica...