During exercise, reflex renal vasoconstriction helps maintain blood pressure and redistributes blood flow to the contracting muscle. Sex and muscle mass have been shown to influence certain cardiovascular responses to exercise. Whether sex and/or muscle mass influence renal vasoconstrictor responses to exercise is unknown. We studied healthy men (n = 10) and women (n = 10) matched for age and b...

Obesity is increasingly recognized as a risk factor for renal disease, but the mechanism is unclear. Renal plasma flow response to captopril, as an index of renin-angiotensin system activity, was measured by para-aminohippurate clearance technique in 100 healthy, normotensive subjects in balance on a high-salt diet. Of the 100 subjects, body mass index exceeded 25 in 56 and exceeded 30 in 22. T...

background: adrenal hematoma is a very rare acquired cause of neonatal hypertension. in this study, we report a case of neonatal hypertension associated with adrenal hematoma. a male neonate was immediately transferred to our neonatal intensive care unit after delivery due to meconium aspiration. he needed to be on mechanical ventilation support. during his hospital stay, hospital records showe...

An abdominal computed tomography scan showed a 3‐cm isodensity and weak contrast‐enhancing but delay‐enhancement solid mass in the right kidney cortex [Figure 1a and 1b]. Renal Doppler was also ordered which revealed normal renal vessels with normal flow pattern. An ultrasonography confirmed a well‐defined rounded and hypoechoic solid mass at the same location. Selective renal arteriography sho...

investigating nozzle’s orifice flow is challenging both experimentally and theoretically. this paper focuses on simulating flow inside diesel injector nozzle via ansys fluent v15. validation is performed with experimental results from winkhofler et al (2001). several important parameters such as mass flow rate, velocity profiles and pressure profiles are used for this validation. results includ...

Tc-99m dimercaptosuccinic acid (DMSA) is used as a renal cortical imaging agent to detect parenchymal abnormalities especially in children. Kidney uptake of DMSA provides an index for evaluation of a functional tubular mass, which depends on the renal blood flow and proximal tubular cell membrane transport function. We here report a boy with renal tubular acidosis, which has noticeably reduced ...

BACKGROUND Children born with reduced congenital renal mass have an increased risk of hypertension and chronic kidney disease in adulthood, although the mechanisms are poorly understood. Similar sequelae occur after fetal uninephrectomy (uni-x) in sheep, leading to a 30% nephron deficit. We hypothesized that renal dysfunction is underpinned by a reduced contribution of nitric oxide (NO) and vas...

Serial measurements of intrarenal distribution of blood flow have been recorded in anesthetized dogs with the (133)xenon "washout" technique. The results showed that normal kidneys redistributed their blood flow after laparotomy and mobilization of the kidney. This alteration consisted of a diminution in percentage of total renal blood flow supplied to the fastest flowing component, and a dimin...

this paper presents a numerical study of local mass transfer coefficients in a 90° bend using the rng version of k–e model to include the influence of curvature on the turbulent transport. simulations were performed for flow through a 90°, 3-d bend for reynolds numbers of 13500, 90000, and 390000, schmidt numbers of 2.53 and 700 and curvature ratios of 1.5, 2, and 2.5. the differences between t...

The xenon washout technique and the renal blood flow response to vasoactive agents or alterations in sodium intake were used to characterize the effect of aging on the renal vasculature in 207 normal human subjects ranging in age from 17 to 76 years. A highly significant, progressive reduction in the mean blood flow, the rapid-component flow rate, and the percent of flow into the rapid-flow (co...