Misoprostol, a prostaglandin E1 derivative, has been widely used in nonpregnant women because of its cervical ripening and uterotonic effects. A large number of studies have demonstrated its effectiveness in enhancing ease of cervical dilation. This review article describes its pharmacokinetic profile and the relationship between prostaglandins and cervical ripening and uterine contraction and ...

OBJECTIVE The purpose of this study was to compare the cost-effectiveness of dilation and evacuation versus misoprostol induction of labor for second-trimester termination. STUDY DESIGN Using decision analysis, we compared the cost-effectiveness of dilation and evacuation and misoprostol induction of labor for second-trimester termination. Complications for dilation and evacuation and inducti...

At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal misoprostol with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 108 pregnant women who had referred t...

at times, despite an unripe cervix, induction of labor may be needed. in these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. the aim of this study is the comparison of vaginal misoprostol with foley catheter for cervical ripening and induction of labor. this randomized clinical trial was performed on 108 pregnant women who had referred t...

background: difficulty in cervical dilatation is a hard situation during the procedure of diagnostic dilatation and curettage in some cases. this study was performed to evaluate the effect of vaginal misoprostol for cervical priming before diagnostic dilatation and curettage. methods: in this study 56 women were selected as the candidates for dilatation and curettage. the study was double blind...

Roughly 11% of induced abortions in the United States are performed after 14 weeks of gestation, most commonly by dilation and evacuation (D&E). For a D&E procedure, the cervix must be dilated sufficiently to allow passage of operative instruments and products of conception without injuring the uterus or cervical canal. Preoperative preparation of the cervix reduces the risk of cervical lacerat...