نتایج جستجو برای: related apoptosis
تعداد نتایج: 1304336 فیلتر نتایج به سال:
Background: Colorectal cancer (CRC) is attributed as one of the most common malignancies worldwide. CD133 molecule, as a pentaspan transmembrane glycoprotein, confers stem cell-related characteristics, including self-renewal and multi-directional differentiation capability. CD133 plays important roles in the progression of CRC by conferring apoptotic resistance and migration ab...
Background: In this study, we evaluated the incidence of apoptosis at the ultrastructural levels and expression of some apoptosis-related genes in vitrified human ovarian tissue just after warming. Methods: Human ovarian tissue biopsies from 23 women after caesarean section were transported to the laboratory within 2 hours, and then they were cut into small pieces. Some pieces were vitrified an...
This study explored the changes in bone marrow CD235a+ nucleated red blood cell apoptosis and signal pathways patients with chronic mountain sickness. We collected data from 21 sickness 20 non-chronic patients. Bone mononuclear cells, flow cytometry is used to detect apoptotic index of cells determine mitochondrial membrane potential; reverse transcription quantitative polymerase chain reaction...
Background: Doxorubicin (DOX)-induced cardiotoxicity appears to be a growing concern for extensive use in acute lymphoblastic leukemia (ALL). The new combination treatment strategies, therefore might be an effective way of decreasing its side effects as well as improving efficacy. AMG232 (KRT-232) is a potential MDM-2 inhibitor, increasing available p53 through disturbing p53-MDM-2 interaction....
In this study, the antioxidative effect of melatonin was investigated in aging retinal pigment epithelial cells vitro. The objective study is to explore administration pharmacological doses for prevention symptoms.Specific concentrations (20 µM, 40 µM and 80 µM) were used treat hydrogen peroxide-induced flow cytometry employed examine cell apoptosis. A specific probe utilized detect intracellul...
Mechanical stimulation is capable of affecting cell apoptosis. Several studies have shown that the Bcl-2 gene family, including and Bax gene, plays an important role in apoptosis, as proteins produced by can inhibit apoptosis while promote Understanding how mechanical alters expression apoptosis-related genes cardiomyocytes contribute to development ways cardiomyocyte necrosis. Intermediate myo...
Neuroblastoma is a disease that observed in early childhood, originating from the sympathetic nervous system and very difficult to treat. Etoposide, topoisomerase 2 inhibitor, one of agents used cancer treatment. Galangin puerarin are plant-based antioxidants with anticancer properties. Since apoptosis induction methods treatment, evaluation mRNA expression levels apoptosis-related genes aimed ...
we have previously shown that the proliferative response of t cells to antigenic or mitogenic stimulus decreased with age and that caloric resection (cr) attenuated the age-related decline in proliferation and il-2 expression. because activation-induced apoptosis is known to regulate cell proliferation and eliminate the high number of activated cells during an immune response, it was of interes...
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