Twenty-one enzymatic activities and red cell glutathione content are compared in cord blood, dyserythropoietic disorders, normal subjects, and subjects with hemolytic syndromes and reticulocytosis approximating that of the newborn. The dyseryth ropoietic states are heterogeneous and include several hereditary disorders, “preleukemia” and overt leukemia, refractory anemia with and without marrow...

Abstract Background Iron-deficiency anemia is a widespread public health problem with major consequences for human health especially, children. However, in a fraction of patients an underlying cause is never found during routine investigation. Recent studies have suggested an association between Helicobacter pylori (H. Pylori) infection and iron-deficiency ...

Successful Treatment of Refractory Autoimmune Hemolytic Anemia (AIHA) in a Child, Based on Iranian Traditional Medicine: A Case Report

Few therapeutic options are available for patients with aplastic anemia who are ineligible for transplantation or refractory to immunosuppressive therapy. Eltrombopag was recently shown to produce trilineage responses in refractory patients. However, the effects of real-life use of this drug remain unknown. This retrospective study (2012-2016) was conducted by the French Reference Center for Ap...

EFRACTORY anemia was omie of the first pathologic effects noted as a result of exposure to radioactive agents. Since the original description, published over forty-five years ago, a number of reports have appeared in the literature describing the occurrence of refractory anemia as a late effect of repeated exposures to x-rays or various radioactive materials.’ ‘ 2 , 3 The susceptibility of the ...

Purpose:Myelodysplastic syndromes (MDS) are a group of disorders characterized by cytopenias, with a propensity for evolution into acute myeloid leukemias (AML). This transformation is driven by genomic instability, but mechanisms remain unknown. Telomere dysfunction might generate genomic instability leading to cytopenias and disease progression. Experimental Design:We undertook a pilot study ...