Objective: Therapeutic drug monitoring (TDM) is the measurement of serum concentrations to optimize pharmacotherapy. Traditionally, blood pressure measurements alone, and not TDM, have been used evaluate antihypertensive response. However, approximately 50 % hypertensive patients treated by lifestyle changes drugs fail achieve control. Serum concentration could be useful select optimal in adjus...

Late pregnancy is accompanied by dramatic changes in the metabolism of sheep, which nutrient requirements increase and metabolic capacity ewes under severe stress due to rapid foetal growth development mammary gland. The blood profile can be used monitor these alterations, lead disorders such as toxaemia. However, data available on serum parameters sheep do not consider physiological state. The...