(1) the secondary stage of freeze - drying, particularly the last day, is not important and i suggest the whole procedure is reduced to three days, the primary stage occupying two of these. (2) the mothod used obtains the satisfactory low level of residual moisture. resume (3) experiments on reconstitution with saline and distilled water show that distilled water is more satisfactory and i sugg...

The timely reconstitution and regain of function of a donor-derived immune system is of utmost importance for the recovery and long-term survival of patients after allogeneic hematopoietic stem cell transplantation (HSCT). Of note, new developments such as umbilical cord blood or haploidentical grafts were associated with prolonged immunodeficiency due to delayed immune reconstitution, raising ...

Immune reconstitution inflammation syndrome typically occurs within days after patients undergo highly active anti-retroviral therapy and is a big hurdle for effective treatment of AIDS patients. In this study, we monitored immune reconstitution inflammation syndrome occurrence in 238 AIDS patients treated with highly active anti-retroviral therapy. Among them, immune reconstitution inflammatio...

Hematopoietic stem cell transplantation (HSCT) is an increasingly common treatment for children with a range of hematological disorders. Conditioning with cytotoxic chemotherapy and total body irradiation leaves patients severely immunocompromised. T-cell reconstitution can take several years due to delayed restoration of thymic output. Understanding T-cell reconstitution in children is complic...

The present paper is a systematic, comparative study on the reconstitution of an apocytochrome b6 purified from a heterologous system using a detergent-free method and reconstitution into liposomes performed using three different detergents: SDS, Triton X-100 and DM, and two methods of detergent removal by dialysis and using Bio-Beads. The product size, its distribution and zeta potential, and ...

The in situ surface reconstitution of a catalyst for hydrogen evolution refers to its structure induced by strong interactions with reaction intermediates during the (HER), which eventually leads self-optimization active sites. In consideration superior performance that can be achieved reconstitution, more and attention has been paid relationship between site HER activity. More and/or operando ...