Introduction: Rathke cleft cysts (RCC’s) are cystic sellar and supra sellar benign lesions which are thought to originate from the remnants of Rathke’s pouch. There are no specific clinical or radiological signs to differentiate them from other pituitary lesions. Presentation of Case: We report a 25-year-old female presented with hyperandrogenism and menstrual disorder, with the preliminary ...

The computed tomographic (CT) and pathologic findings in three cases of intraand suprasellar epithelial cysts (symptomatic Rathke cleft cysts) are described. Literature review revealed that the characteristic CT finding is an intra sellar and/or suprasellar low-density mass that mayor may not be enhanced. The enhancement is ringlike or capsular in nature. Whether the cyst wall is enhanced or no...

a large rathke's cyst was marsupialized into the sphenoid sinus of a 45-year old woman who presented with headache, polydipsia, cessation of menses and diplopia. a brief review of cases is presented.

This study used mouse models to investigate the role of LIM homeodomain transcription factor Isl1 in pituitary development. It reveals that has multiple, critical roles gland Pituitary-specific deletion caused hypopituitarism with increased stem cell apoptosis, reduced both differentiation thyrotropes and gonadotropes body size, even promoted development multiple Rathke’s cleft-like cysts.

H. Megdiche-Bazarbacha K. Ben Hammouda A.B. Aicha R. Sebai L. Belghith M. Khaldi S. Touibi SUMMARY: Symptomatic Rathke cleft cysts (RCC) are reported in the sellar and suprasellar regions, but no case of sphenoidal RCC has been reported. We report a case of sphenoidal RCC in a 41-year-old man. The lesion was revealed by headaches and diplopia. Symptoms disappeared transiently after a spontaneou...