AIMS Medicinal plants are increasingly being projected as suitable alternative sources of antiviral agents. The development of a suitable in vitro pharmacodynamic screening technique could contribute to rapid identification of potential bioactive plants and also to the standardization and/or pharmacokinetic-pharmacodynamic profiling of the bioactive components. METHODS AND RESULTS Recombinant...

Lichen symbioses are microecosystems hosting many other living organisms besides the two major lichen symbionts (i.e., lichenized fungi [the mycobiont] and green microalgae or cyanobacteria photobiont]). Recent investigations evidenced that fungi, non-photosynthetic bacteria, co-inhabit within thalli, but their diversity roles still underinvestigated. Here we present an ad hoc stratified sampli...

Liquid chromatography coupled with mass spectrometry is an outstanding methodology for fast analysis of phenolic compounds in biological samples. Twenty two compounds were quickly and accurately identified in the methanolic extract of the Antarctic lichen Ramalina terebrata for the first time using ultra high pressure liquid chromatography coupled with photodiode array detector and high resolut...

The current literature reveals that the intrathalline coexistence of multiple microalgal taxa in lichens is more common than previously thought, and additional complexity is supported by the coexistence of bacteria and basidiomycete yeasts in lichen thalli. This replaces the old paradigm that lichen symbiosis occurs between a fungus and a single photobiont. The lichen Ramalina farinacea has pro...

Plants are rich in bioactive chemical secondary metabolites and have proven insecticidal activity by killing or repelling insects. In this work, we aim to evaluate the direct delayed effects of ethanolic plant extracts on vinegar fly (Drosophila melanogaster). The treatment was performed ingestion second instar larvae (L2) impact extract development for 15 days subsequently feeding behavior lar...

In vitro, the photoprotective, cytotoxic and photomodifying properties of hexane benzene extracts from widely distributed in Belarus lichens Cladonia arbuscula, Evernia prunastri, Hypogymnia physodes, Ramalina pollinaria Xanthoria parietina culture human keratinocytes (HaCAT), are estimated. It was found that these not they have a effect upon irradiation keratinocyte cultures with ultraviolet l...