Radiotracers play an important role in interrogating molecular processes both in vitro and in vivo. However, current methods are limited to measuring average radiotracer uptake in large cell populations and, as a result, lack the ability to quantify cell-to-cell variations. Here we apply a new technique, termed radioluminescence microscopy, to visualize radiotracer uptake in single living cells...

A 65 year-old overweight man with a history of prostate cancer was referred to our nuclear medicine department for bone scanning. Anterior projection images showed two small foci of increased radiotracer uptake corresponding to the anterior arcs of the right and left sixth ribs, which were interpreted as suspicious for metastatic involvement. Eight months later the patient was referred for foll...

UNLABELLED Despite intense efforts to develop radiotracers to detect cancers or monitor treatment response, few are widely used as a result of challenges with demonstrating clear clinical use. We reasoned that a radiotracer targeting a validated clinical biomarker could more clearly assess the advantages of imaging cancer. The virtues and shortcomings of measuring secreted prostate-specific ant...

We reported a 35 year old breast cancer patient who was referred to our nuclear medicine department for sentinel node mapping. She was planned to undergo mastectomy and lymphatic mapping. A dose of Tc-99m Phytate was injection in the peri-areolar region in an intra-dermal fashion. Two hours post-injection no sentinel node was visible in the axilla. Due to a high liver uptake, inadvertent intra-...

background: sentinel node biopsy (slnb) is the standard of care for breast cancer treatment and it is getting wide acceptance in iran. the radiation safety of the procedure has been investigated under controlled conditions, but the standard dose of radiotracer and techniques are not always observed in the community setting. the aim of this study was to assess the magnitude of the absorbed doses...

a 65 year-old overweight man with a history of prostate cancer was referred to our nuclear medicine department for bone scanning. anterior projection images showed two small foci of increased radiotracer uptake corresponding to the anterior arcs of the right and left sixth ribs, which were interpreted as suspicious for metastatic involvement. eight months later the patient was referred for foll...

Abstract Background Accurate sentinel lymph node (SLN) staging is essential for both prognosis and treatment in patients with breast cancer. However, the preoperative lymphoscintigraphy may fail to visualize SLN some patients. The purpose of this retrospective study was identify risk factors associated nonvisualization on lymphoscintigraphy. For single-center study, all data procedures from Mar...

objectives : microbial leakage through the implant-abutment (i-a) interface results in bacterial colonization in two-piece implants. the aim of this study was to compare microleakage rates in three types of replace abutments namely snappy, goldadapt, and customized ceramic using radiotracing. materials and methods: three groups, one for each abutment type, of five implants and one positive and ...

FOREWORD The Coordinated Research Project (CRP) on Radiotracer Technology for Engineering Unit Operation Studies and Unit Process Optimization was carried out by the International Atomic Energy Agency (IAEA) from December 1997 until December 2000. The project developed and validated procedures and protocols for investigation of major industrial processes, including fluidized beds, sugar crystal...