Protection of Escherichia coli NIHJ and C57BL mice from the effects of 60Co gamma-rays provided by S-alk(en)yl-L-cysteines and their hydantoin derivatives was examined. E. coli (10(6) cells/ml) suspended in a 20 mM aqueous solution of one of the drugs was irradiated with 60 Gy of gamma-rays. Five week-old male mice were exposed to 5.0-9.5 Gy of gamma-rays after a single intraperitoneal injectio...

This is the second article published in the Trees for Life Journal which deals with radioprotection (see http://www. tfljournal.org/article.php/2007042416194363 by Sancheti and Goyal). While it is not a major focus of this journal, radioprotection has interest for our readership and is attracting ever more attention within the scientific community. No synthetic radioprotective chemicals are ava...

Using rat liver mitochondria as model systems, we examined the radioprotective and antioxidant effects of the Indian medicinal plant Terminalia arjuna. Various sohxlet fractions of the bark and the medicinal formulation arjunsal besides an active ingredient, baicalein, were examined for their ability to protect both rat liver mitochondria and cardiac homogenate against radiation and oxidative s...

We have examined the in vivo radioprotective effects of the macrocyclic lactone protein kinase C (PK-C) activator, bryostatin 1, administered either alone or in conjunction with recombinant murine granulocyte-macrophage colony-stimulating factor (rmGM-CSF), in Balb/c and C3H/HeN mice subjected to lethal total body irradiation (TBI). When administered alone on a divided dose schedule (24 hours a...

The aim of the present study was to investigate whether pyrroloquinoline quinine (PQQ) serve a radioprotective role in parotid gland damage induced by total body irradiation (TBI) in C57BL/6J mice. A total of 15 female 8-week-old C57BL/6J mice were randomly assigned into three treatment groups: i) Untreated control (no irradiation); ii) 4 gray (Gy) X-ray irradiation; iii) 4 Gy X-ray irradiation...