STUDY OBJECTIVES To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN Patients with HHT had serial measurements of the following: (1) arterial oxygen saturation (SaO2) by pulse oximetry in erect and sup...

BACKGROUND There is now increasing evidence to support the use of indocyanine green (ICG) for sentinel lymph node (SLN) detection in early breast cancer. The primary objective of this feasibility study (ICG-10) was to determine the sensitivity and safety of ICG fluorescence imaging in sentinel lymph node identification when combined with blue dye and radiocolloid. METHODS One hundred women wi...

A comparison has been made of the radioisotope dilution-coated charcoal method and a microbiological assay (with L. leichmannii as test organism) for determining the concentration of vitamin B(12) in serum. A satisfactory correlation was found between the results of the two methods. Under appropriate conditions the reproducibility of the radioisotope method compared favourably with that of the ...

The assumptions of conventional whole-rock and mineral isochron radioisotope dating were tested using a suite of radioisotopes from two Precambrian rocks. Amphibolite from the Beartooth Mountains of Wyoming shows evidence of thorough metamorphism by isochemical processes from andesite by an early Precambrian magma-intrusion event. A diabase sill, exposed within the wall of Grand Canyon at Bass ...