Radiation necrosis of the brain (BRN) is most frequent and dangerous iatrogenic complication radiation therapy tumors non-tumor diseases base skull. The risk its development increases with an increase in amount radiation, single total doses due to synergy action adjuvant chemotherapy used. pathogenesis BRN based on damage microcirculatory bed tumor surrounding tissues edema impaired trophic neu...

PURPOSE To describe both the common and less frequently encountered magnetic resonance (MR) imaging features of radiation therapy- and chemotherapy-induced brain injury, with particular emphasis on radiation necrosis. MATERIALS AND METHODS A cohort of 148 adult patients underwent surgical resection of malignant brain (glial) tumors and were subsequently entered into a research protocol that c...

OGAWA, T., UEMURA, K., KANNO, I., SHISHIDO, F., INUGAMI, A., YAMAGUCHI, T., MURAKAMI, M., HIRATA, K., KATO, T., MINEURA, K. and KOWADA, M. Delayed Radiation Necrosis of Brain Evaluated Positron Emission Tomography. Tohoku J. exp. Med., 1988, 155 (3), 247-260 In four patients highly suspected of having delayed radiation necrosis of the brain, regional cerebral blood flow and metabolism were stud...

BACKGROUND Distinction between radiation necrosis and recurrence of intraparenchymal tumors is necessary to select the appropriate treatment, but it is often difficult based on imaging features alone. We developed an algorithm for analyzing magnetic resonance spectroscopy (MRS) findings and studied its accuracy in differentiation between radiation necrosis and tumor recurrence. METHODS Thirty...

BACKGROUND Discrimination between radiation necrosis and tumor progression after radiation therapy represents a radiologic challenge. The aim of our investigation is to identify patterns of radiation necrosis on brain magnetic resonance imaging (MRI) and positron emission tomography (PET) with Fluoroethyltyrosin (FET) after proton beam therapy (PBT) for skull base tumors. MATERIAL AND METHODS...

The clinical, radiologic, and pathologic findings in radiation injury of the brain are reviewed. Late radiation injury is the major, dose-limiting complication of brain irradiation and occurs in two forms, focal and diffuse, which differ significantly in clinical and radiologic features. Focal and diffuse injuries both include a wide spectrum of abnormalities, from subclinical changes detectabl...

Because nasopharyngeal carcinoma has a high frequency of intracranial spread, adequate radiation treatment inevitably results in irradiation of the temporal lobes. A 38-year-old woman who was treated for nasopharyn-geal carcinoma 30 months previously and had been given radiation therapy (70 Gy to the primary site) presented with headaches. Computed tomography (CT) showed an enhancing lesion in ...

There are very few cases of radiation-induced femoral head necrosis described in the literature, therefore, this case will add new knowledge and highlights important aspects in the diagnosis and management of this uncommon condition. Our patient was 74 years old and presented with left hip and groin pain for 8 months, with no previous history of trauma or osteoarthritis. However, he had been tr...