نتایج جستجو برای: radiation mitigation

تعداد نتایج: 270118  

2014
Mary Anne Dell

With the advent of high-energy collimators and dual-head coincidence cameras, standard nuclear medicine facilities will soon begin imaging with PET isotopes. The use of 511keV emitters raises new radiation safety concerns for technologists traditionally limited to handling mTc and other low-energy isotopes. This article is a basic review of positron emitters, measurement concerns, exposure rate...

Journal: :Journal of nuclear medicine technology 1997
M A Dell

With the advent of high-energy collimators and dual-head coincidence cameras, standard nuclear medicine facilities will soon begin imaging with PET isotopes. The use of 511-keV emitters raises new radiation safety concerns for technologists traditionally limited to handling 99mTc and other low-energy isotopes. This article is a basic review of positron emitters, measurement concerns, exposure r...

2012
Shubhankar Suman Manoj Maniar Albert J Fornace Kamal Datta

BACKGROUND Ionizing radiation-induced hematopoietic injury could occur either due to accidental exposure or due to diagnostic and therapeutic interventions. Currently there is no approved drug to mitigate radiation toxicity in hematopoietic cells. This study investigates the potential of ON 01210.Na, a chlorobenzylsulfone derivative, in ameliorating radiation-induced hematopoietic toxicity when...

Journal: :Progress in Nuclear Science and Technology 2014

2012
Sanath Kumar

More than half of all cancer patients receive radiotherapy as a part of their treatment. With the increasing number of long-term cancer survivors, there is a growing concern about the risk of radiation induced second malignant neoplasm [SMN]. This risk appears to be highest for survivors of childhood cancers. The exact mechanism and dose-response relationship for radiation induced malignancy is...

2004
M. Stettler M. Caffrey P.Graham J. Krone

Field Programmable Gate Array devices have become the technology of choice in small volume modern instrumentation and control systems. These devices have always offered significant advantages in flexibility, and recent advances in fabrication have greatly increased logic capacity, substantially increasing the number of applications for this technology. Unfortunately, the increased density (and ...

Journal: :Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2012
Naomi E Vaughan Timothy M Lenton

We use a simple carbon cycle-climate model to investigate the interactions between a selection of idealized scenarios of mitigated carbon dioxide emissions, carbon dioxide removal (CDR) and solar radiation management (SRM). Two CO(2) emissions trajectories differ by a 15-year delay in the start of mitigation activity. SRM is modelled as a reduction in incoming solar radiation that fully compens...

2011
Joel S. Greenberger David Clump Valerian Kagan Hülya Bayir John S. Lazo Peter Wipf Song Li Xiang Gao Michael W. Epperly

Mitochondrial targeted radiation damage protectors (delivered prior to irradiation) and mitigators (delivered after irradiation, but before the appearance of symptoms associated with radiation syndrome) have been a recent focus in drug discovery for (1) normal tissue radiation protection during fractionated radiotherapy, and (2) radiation terrorism counter measures. Several categories of such m...

Journal: :Chemistry & biology 2015
Renukadevi Patil Erzsébet Szabó James I Fells Andrea Balogh Keng G Lim Yuko Fujiwara Derek D Norman Sue-Chin Lee Louisa Balazs Fridtjof Thomas Shivaputra Patil Karin Emmons-Thompson Alyssa Boler Jur Strobos Shannon W McCool C Ryan Yates Jennifer Stabenow Gerrald I Byrne Duane D Miller Gábor J Tigyi

Pharmacological mitigation of injuries caused by high-dose ionizing radiation is an unsolved medical problem. A specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2) 2-[4-(1,3-dioxo-1H,3H-benzoisoquinolin-2-yl)butylsulfamoyl]benzoic acid (DBIBB) when administered with a postirradiation delay of up to 72 hr reduced mortality of C57BL/6 mice but not L...

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