Animal rabies control has been frustrated by the existence of multiple wildlife reservoirs and the lack of efficacious oral vaccines. In this investigation, raccoons fed a vaccinia-rabies glycoprotein recombinant virus in a sponge bait developed rabies virus-neutralizing antibody (0.6-54.0 units) and resisted street rabies virus infection 28 and 205 days after feeding. Additional raccoons immun...

dear editor:   sir, rabies is an important neurological infection. it is deadly and it is not possible to treat it. despite the attempt for rabies control via animal control and rabies vaccination, there are many reported cases of rabies in each year. basically, the transmission of rabies is due to animal bite. recently, the new mode of rabies transmission, human to human, via transplantation i...

rabies is a fatal neurological infection caused by rabies virus. the deadly rabies virus could enter into human body via the wound that has caused by mammal bite. since rabies is a fatal disease without existing effective treatment, the best way is prevention. the widely examined preventive method for rabies is the use of post exposure rabies vaccination. in this specific case report, the autho...

Background: Rabies virus (RABV) is a deadly neurotropic virus that causes the disease of rabies in humans and animals. L protein is one of the large structural protein of rabies virus, which displays multiple enzymatic activities, and is required for viral transcription and replication. Objectives: A truncated L protein of Rabies virus is being cloned, expressed and purified to produce relevant...

Previous reports strongly suggest that, in addition to the nicotinic acetylcholine receptor, rabies virus can use other, as-yet-unidentified receptors. We found that laboratory cell lines susceptible to rabies virus infection express the neural cell adhesion molecule (NCAM) (CD56) on their surface, whereas resistant cells do not, supporting the idea that NCAM could be a rabies virus receptor. W...

Introduction: Grenada is a rabies endemic country, where terrestrial rabies is maintained in the small Indian mongoose (Herpestes auropunctatus). The role of bats in the epidemiology of rabies in Grenada is unknown. A 1974 report described one rabies virus positive Jamaican fruit bat (Artibeus jamaicensis), and a high seroprevalence in this species. In the current study, the natural exposure to...

Rabies virus exists in dogs on Sri Lanka as a single, minimally divergent lineage only distantly related to other rabies virus lineages in Asia. Stable, geographically isolated virus populations are susceptible to local extinction. A fully implemented rabies-control campaign could make Sri Lanka the first Asian country in >30 years to become free of rabies virus.

Rabies, a negative strand RNA virus belonging to the genus Lyssavirus has existed since hundreds of years. Available historical texts called it 'an ancient curse'. From Aristotle in fourth century BC present day, rabies various species animals. Modern day molecular epidemiology proven evolving nature virus. The showcases considerable genetic plasticity and hence still exists as tangible threat ...

Between 1956 and 1977, 4 human cases of rabies virus infection were attributed to aerosolized rabies virus; however, little work has been done to address this topic since the late 1960s. Employing modern nebulization equipment coupled with serologic, cell culture, and molecular technology, we have continued the investigation into aerosolized rabies virus as a potential route of transmission. La...

BACKGROUND Rabies is a global fatal infectious viral disease that is characterized by a high mortality after onset of clinical symptoms. Recently, there has been an increase in the incidence of rabies in China. The aim of this study was to investigate the incidence of human rabies and characterize the rabies virus nucleoprotein gene in dogs sampled from Fujian Province, Southeast China from 200...