Cancer-associated retinopathy (CAR) is a rare paraneoplastic syndrome, and the recoverin-specific autoantibody is suggested to contribute to the pathogenesis of retinopathy, including apoptosis of retinal cells. Because it is known that CAR(+) cancer patients have a preferable prognosis, we hypothesized that aberrantly expressed recoverin in cancer cells can become a target of cytotoxic T lymph...

In bacterial photosynthesis reaction center-light-harvesting 1 (RC-LH1) complexes trap absorbed solar energy by generating a charge separated state. Subsequent electron and proton transfers form a quinol, destined to diffuse to the cytochrome bc1 complex. In bacteria such as Rhodobacter (Rba.) sphaeroides and Rba. capsulatus the PufX polypeptide creates a channel for quinone/quinol traffic acro...

A critical feature of the intermolecular contacts that bind DNA to the histone octamer is the series of histone arginine residues that insert into the DNA minor groove at each superhelical location where the minor groove faces the histone octamer. One of these "sprocket" arginine residues, histone H4 R45, significantly affects chromatin structure in vivo and is lethal when mutated to alanine or...

Phage 34 transduces some R factors to Proteus mirabilis strain 13. These transductants can transmit the R factor by conjugation. Transduction frequencies vary from I x I ~-~/plaque-forming unit (p.f.u.) adsorbed (higher than .chromosomal marker transduction) to 5 x Io-8/p.f.u. adsorbed. Transduced drug resistance markers of other R factors were detected only in the presence of resident$factors ...

Lee, Sunghou, Zheng Wu, Kathryn Sandberg, S-E. Yoo, and Christine Maric. Posttranscriptional mechanisms contribute to osmotic regulation of ANG type 1 receptors in cultured rat renomedullary interstitial cells. Am J Physiol Regul Integr Comp Physiol 290: R44–R49, 2006. First published August 11, 2005; doi:10.1152/ajpregu.00476.2005.—Previously, we showed that ANG II receptors in cultured rat re...

Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia/lymphoma (ATL) and is associated with a variety of lymphocyte-mediated disorders. HTLV-1 transmission occurs by transmission of infected cells via breast-feeding by infected mothers, sexual intercourse, and contaminated blood products. The route of exposure and early virus replication events are believed to be key...

Williams DB, Wan Z, Frier BC, Bell RC, Field CJ, Wright DC. Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats. Am J Physiol Regul Integr Comp Physiol 302: R49–R58, 2012. First published October 26, 2011; doi:10.1152/ajpregu.00304.2011.—Glucocorticoid excess induces marked insulin resistance and glucose intolerance. A recent study has shown...

Abstract Introduction Student-athletes’ time demands include scholastic, athletic, and social events that may influence sleep duration; the association between duration, athletic performance, injury risk are inconclusive. Further, limited research investigates long-term habitual patterns in collegiate student-athletes. We aimed to describe feasibility of monitoring self-reported within-person d...

Abstract Introduction Psychosocial stress exposure during the first 18 years of life promotes adverse sleep and cardiometabolic health effects. The purpose study was to investigate relationships between childhood (CS), efficiency (SE), fasting glucose levels (FG) in young adulthood. Methods In 24 adults ages 35 (83% Female; mean±SD, age = 24±5 y), CS assessed using a retrospective assessment av...

The quasistationary quasienergy state approach (QQES) is applied to the analysis of partial (n-photon) decay rates and angular distributions (ADs) of photoelectrons produced by an elliptically polarized laser field. The problem is formulated for a weakly bound electron with an energy E0 in the threedimensional δ-model potential (which approximates the short-range potential of a negative ion) in...