نتایج جستجو برای: quantitative magnetization transfer imaging qmti
تعداد نتایج: 1039931 فیلتر نتایج به سال:
At least 85% of individuals with multiple sclerosis report walking dysfunction as their primary complaint. Walking and strength measures are common clinical measures to mark increasing disability or improvement with rehabilitation. Previous studies have shown an association between strength or walking ability and spinal cord MRI measures, and strength measures with brainstem corticospinal tract...
It is generally accepted that signal formation in balanced steady-state free precession (bSSFP) is a simple function of relaxation times and flip angle only. This can be confirmed for fluids, but for more complex substances, magnetization transfer (MT) can lead to a considerable loss of steady-state signal. Thus, especially in tissues, the analytical description of bSSFP requires a revision to ...
Purpose: To increase the efficiency of densely encoded magnetization transfer imaging of the brain, we time-multiplex multiple slices within the same readout using simultaneous echo refocusing FLASH imaging with magnetization transfer (MT) preparation (MT-SER-FLASH). Materials and Methods: Inefficiency in total scan time results from the number of frequency samples needed for sufficient quality...
Inversion recovery sequences that vary the inversion time (t(i)) have been employed to determine T(1) and, more recently, quantitative magnetization transfer parameters. Specifically, in previous work, the inversion recovery pulse sequences varied t(i) only while maintaining a constant delay (t(d)) between repetitions. T(1) values were determined by fitting to a single exponential function, and...
Human prion diseases are fatal neurodegenerative disorders caused by misfolding of the prion protein. There are no useful biomarkers of disease progression. Cerebral cortex spongiform change, one of the classical pathological features of prion disease, resolves in prion-infected transgenic mice following prion protein gene knockout. We investigated the cross-sectional, longitudinal and post-mor...
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