the efficiency of three statistical models, ahp surface-weighted density bivariate (semi-quantitative models), stepwise multivariate regression and logistic multivariate regression models were compared in chehel-chai watershed in golestan province, iran. in current study the hazard map was prepared according to the top model of landslide hazard map. chehel-chai watershed is located as one of go...

As a promising tool for dissecting the genetic basis of common diseases, expression quantitative trait loci (eQTL) study has attracted increasing research interest. The traditional eQTL methods focus on testing the associations between individual single-nucleotide polymorphisms (SNPs) and gene expression traits. A major drawback of this approach is that it cannot model the joint effect of a set...

Deep characterization of molecular function of genetic variants in the human genome is becoming increasingly important for understanding genetic associations to disease and for learning to read the regulatory code of the genome. In this paper, I discuss how recent advances in both quantitative genetics and molecular biology have contributed to understanding functional effects of genetic variant...

Quantitative genetics (QG) analyses variation in traits of humans, other animals, or plants in ways that take account of the genealogical relatedness of the individuals whose traits are observed. This article focuses on "classical" QG where the analysis of variation does not involve data on measurable genetic or environmental entities or factors. Classical QG analysis employs models of genes wi...

secreted cytokines of th1 (t-helper)/th2 cells play an important role in the pathogenesis of many diseases. th1 cells secrete predominantly ifn-γ and il-2 which regulate cell-mediated immunity against intracellular pathogens and tumors. in this study, expression of ifn-γ was studied using semiquantitative rt-pcr. in brief, lymphocytes of a healthy donor were stimulated with pha (1μg/106 cell/ml...

An important step in plant breeding programs is identification of parents that are geneticallydistant from each other, to find crossing combinations with better prospects of hybrid vigor. Thepotential of identifying genetically distant parents depends on genetic diversity of population. 58 linesof rice from diverse origins have been employed to study genetic variation in order to identify themo...

purpose: to evaluate the agreement between a new method for quantitative analysis of fundus or angiographic images using photoshop software and clinical judgment. methods: four hundred eighteen fundus and angiographic images of diabetic patients were evaluated by three retina specialists and then by computer using photoshop 7.0 software. four variables were selected for comparison: amount of ha...

objective: the present study was carried out to examine the efficacy of psychoneurotherapy (pnt) on reducing symptoms severity in treatment-naïve patients with obsessive-compulsive washing. this study evaluated a new form of psychotherapy based on neurobiological model of obsessive-compulsive disorder (ocd).  methods: the study was conducted as a quasi-experimental research. the statistical pop...

I argue that the g factor meets the fundamental criteria of a scientific construct more fully than any other conception of intelligence. I briefly discuss the evidence regarding the relationship of brain size to intelligence. A review of a large body of evidence demonstrates that there is a g factor in a wide range of species and that, in the species studied, it relates to brain size and is her...

The purpose of this article is to present the value of using quantitative genetic approaches to understanding individual differences and ethnic diversity in aging. There are three major points to be discussed: 1) the difference between race and ethnicity, 2) inter-versus intra-group differences, and 3) the contribution of quantitative genetics methods to understanding individual variation withi...