Prostate carcinoma presenting as symptomatic metastases to atlantoaxial spine is extremely rare. Spastic quadriparesis due to pathological fracture of odontoid as the only initial manifestation without symptoms of primary malignancy is rarer still. We report a 64-year-old male who presented with progressive spastic quadriparesis along with urinary retention of 3 weeks duration. Computed tomogra...

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease, causing multifocal CNS inflammation affecting the optic nerves & spinal cord. In 20th century, ‘Devics disease’ was considered as variant of Multiple sclerosis(MS) that spared brain. However, discovery IgG-class antibodies bind to water channel aquaporin-4 (AQP4-IgG) in serum from patients with Devic’s but not thos...

We present the case of 36 yrs old female who presented with acute onset quadriparesis who was subsequently diagnosed to have Sjogrens syndrome with distal RTA with hypothyroidism.