The QCD factorization approach provides the theoretical basis for a systematic analysis of nonleptonic decay amplitudes of B mesons in the heavy-quark limit. After recalling the basic ideas underlying this formalism, several tests of QCD factorization in the decays B → D(∗)L, B → K∗γ, and B → πK,ππ are discussed. It is then illustrated how factorization can be used to obtain new constraints on ...