Peters and Sinclair (1933) have shown that in pigeons suffering from vitamin-B, deficiency the brain, when incubated with lactic acid, produced pyruvic acid in appreciable amount whereas when the brain of normal control birds is substituted this is not produced. Peters and Thompson (1934) further showed that pyruvic acid is probably a normal intermediary in the course of carbohydrate metabolism...

Eagon, R. G. (University of Georgia, Athens), and H. W. Cho. Major products of glucose dissimilation by Pseudomonas natriegens. J. Bacteriol. 89:1209-1211. 1965.-Pseudomonas natriegens aerobically catabolized glucose to yield predominantly acetic acid, pyruvic acid, and CO(2), whereas little or no lactic acid was formed. Under anaerobic conditions, glucose in an enriched medium was fermented to...

[1] Aqueous-phase oxidation (in clouds and aerosols) is a potentially important source of organic aerosol and could explain the atmospheric presence of oxalic acid. Methylglyoxal, a water-soluble product of isoprene, oxidizes further in the aqueous phase to pyruvic acid. Discrepancies in the literature regarding the aqueous-phase oxidation of pyruvic acid create large uncertainties in the inclo...

keto-enol tautomerism was investigated for ionized pyruvic acid using the dft(b3lyp) method and the larger basis sets [6-31++g(d,p), 6-311++g(3df, 3pd) and aug-cc-pvdz]. change of the tautomeric preference was observed when going from the neutral to ionized tautomeric mixture. ionization favors the enolization process (ketoenol) of pyruvic acid, whereas the ketonization (ketoenol) is preferred ...

The method used for the synthesis of labeled pyruvic acid as reported in the preceding communication (1) involved the isolation of labeled pyruvamide as an intermediate and suggested an investigation of the fate of this compound in relation to pyruvic acid. Pyruvamide showed a marked difference from pyruvic acid in its metabolic behavior. In addition, an experiment with labeled acetamide was ca...

IN the course of recent work on the role of vitamin B, in the metabolism of brain, it was discovered [Peters and Sinclair, 1933] that lactate solutions in which avitaminous pigeon's brain cells had respired for 2 hours gave a positive nitroprusside reaction for pyruvic acid [Simon and Piaux, 1924]. This led to a quantitative investigation of the formation of pyruvic acid during the respiration ...

THE problem of the specificity of the pyruvate oxidation system in pigeon's brain tissue has been studied more fully by us, not only in the hope that it would throw fresh light upon the path of complete oxidation of pyruvic acid, but also in the belief that knowledge of the behaviour of other simple oc-ketoacids would contribute further to the elucidation of the metabolism of some of the oxidat...

Thiamin, acting in the form of its phosphoric ester co-carboxylase, is an enzyme necessary for the complete metabolism of glucose. In its absence glucose is broken down as far as pyruvic acid, which then accumulates until vitamin B1 is supplied. Peters and Thompson (1934) and Peters (1936) demonstrated that the respiration of avitaminotic pigeon brain was reduced as compared with that of normal...