Traditional herbal drugs have a great demand in under developed countries due to their efficacy, low cost and lesser adverse effects, and they are considered to be “natural. Aloe vera at the dose of 500 mg body weight per oral was studied for the gross toxicities and hepatoprotective effect and observed the level of liver biochemical parameters in rabbits. Aloe vera showed highly significant (p...

It is well known that isotopic tracer st,udies of a complex system of interrelated reactions can determine the existence and magnitude of reaction sequences for transferring atoms from a given reactant to a particular product and also in many cases, usually through studies involving asymmetrically labeled reactants and including degradation of the products, establish parameters with which postu...

During anaerobic growth of bacteria, organic intermediates of metabolism, such as pyruvate or its derivatives, serve as electron acceptors to maintain the overall redox balance. Under these conditions, the ATP needed for cell growth is derived from substrate-level phosphorylation. In Escherichia coli, conversion of glucose to pyruvate yields 2 net ATPs, while metabolism of a pentose, such as xy...

One of the unique characteristics of polymorphonuclear leukocytes from normal subjects is their high rate of aerobic and anaerobic glycolysis with accumulation of lactic acid (1,2). Intermediates and enzymes of the Embden-Meyerhof scheme have been isolated and identified (3-5) and Beck (6) has calculated the V,,, of a number of these enzymes. The results indicate the hexokinase to be the chief ...

The enol tautomers of the aromatic oc-keto acids combine instantaneously and reversibly with borate to form complexes of a mixed ester-anhydride structure, thereby displacing the apparent keto-enol equilibrium in favor of the enol tautomer. The enol tautomer and its borate complex have strong absorption in the 300 ml* region (1). This strong absorption is the basis of the spectrophotometric met...

One of the unique characteristics of polymorphonuclear leukocytes from normal subjects is their high rate of aerobic and anaerobic glycolysis with accumulation of lactic acid (1,2). Intermediates and enzymes of the Embden-Meyerhof scheme have been isolated and identified (3-5) and Beck (6) has calculated the V,,, of a number of these enzymes. The results indicate the hexokinase to be the chief ...