Pyoderma gangrenosum is a rare but significant cause of ulcerations. It is a diagnosis of exclusion. Herein, we suggest diagnostic criteria and some historical perspectives on the diagnosis of pyoderma gangrenosum.

1. Gonzalez-Moreno J, Ruiz-Ruigomez M, Callejas Rubio JL, et al. Pyoderma gangrenosum and systemic lupus erythematosus: a report of five cases and review of the literature. Lupus 2015;24:130-7. 2. Schoemann MB, Zenn MR. Pyoderma gangrenosum following free transverse rectus abdominis myocutaneous breast reconstruction: a case report. Ann Plast Surg 2010;64:151-4. 3. Tuffaha SH, Sarhane KA, Mundi...

Pyoderma gangrenosum is a rare idiopathic skin disease. It affects mainly adults, and only 4% of the cases are diagnosed on children and adolescents. There are four clinical forms of pyoderma gangrenosum: ulcerative, pustular, bullous, and vegetative (superficial granulomatous pyoderma). Superficial granulomatous pyoderma is considered the most benign and uncommon form of the disease. Patients ...

Pyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There h...

Pyoderma gangrenosum is an uncommon and recurrent neutrophilic dermatosis of unknown cause. The lesions usually start as tender sterile papulopustules or erythematous nodules that undergo necrosis followed by ulceration. The lower limbs are most commonly affected and around half of the cases are associated with systemic disorders. Although rare, cases of pyoderma gangrenosum with extramucocutan...

INTRODUCTION Pyoderma gangrenosum is a rare clinical entity of poorly understood pathogenesis, characterized by rapidly progressing skin necrosis. In around half of patients pyoderma gangrenosum is a manifestation of underlying systemic diseases, such as rheumatoid arthritis, inflammatory bowel disease or myeloproliferative disorders. There have been very few reports on the association of pyode...

1 Wilson-Jones E, Winkelmann RK. Superficial granulomatous pyoderma: a localised vegetative form of pyoderma gangrenosum. J Am Acad Dermatol, 1988; 18:511–21. 2 Winkelmann RK, Wilson-Jones E, Gibson LE, Quimby SR. Histopathology features of superficial granulomatous pyoderma. J Dermatol, 1989; 16:127–32. 3 Lichter MD, Welykj SE, Gradini R, Solomon LM. Superficial granulomatous pyoderma. Int J D...

BACKGROUND Pyoderma gangrenosum is a rare ulcerative skin disease. The diagnosis is based on clinical features and excluding other causes of skin ulcers, as it does not have characteristic histopathology or laboratory findings. The etiology is poorly understood. Lesions can develop spontaneously, after surgery or after trauma. CASE PRESENTATION We present the case of a 32-year-old woman with ...

OBJECTIVE To highlight the key differences in history, examination, and management of pyoderma gangrenosum and necrotizing fasciitis and to outline the importance of distinguishing these 2 conditions. METHOD We present a case report of a gentleman with a background of ulcerative colitis having a 1-week history of an erythematous wound and localized abscess to the right leg that failed to resp...

Pyoderma gangrenosum is an autoimmune disease of the skin that causes enlarging, painful ulcers with ragged, undermined, purplish borders. Pyoderma gangrenosum is frequently mistaken for other conditions, and early diagnosis is essential to avoid disfiguring surgery and prolonged recovery. We report a case of pyoderma gangrenosum in a patient with psoriatic arthritis that was initially treated ...